Effects of auricular acupuncture on cholecytokinin in cerebral cortex of sprague dawley rats

이침(耳鍼)이 절식(絶食)시킨 흰쥐의 대뇌피질(大腦皮質)에서 CCK 활성변화(活性變化)에 미치는 영향(影響)

  • Kim, Ee-Hwa (Department of Meridianology, College of Oriental Medicine, Semyung University) ;
  • Kim, Youn-Jung (Kohwang Medical Research Institute, Kyung-Hee University) ;
  • Lim, Baek-Vin (Kohwang Medical Research Institute, Kyung-Hee University) ;
  • Jang, Mi-Hyun (Kohwang Medical Research Institute, Kyung-Hee University) ;
  • Chung, Joo-Ho (Kohwang Medical Research Institute, Kyung-Hee University) ;
  • Kim, Chang-Ju (Kohwang Medical Research Institute, Kyung-Hee University)
  • 김이화 (세명대학교 한의과대학 경혈학교실) ;
  • 김연정 (경희대학교 고황의학연구소) ;
  • 임백빈 (경희대학교 고황의학연구소) ;
  • 장미현 (경희대학교 고황의학연구소) ;
  • 정주호 (경희대학교 고황의학연구소) ;
  • 김창주 (경희대학교 고황의학연구소)
  • Received : 2000.08.10
  • Accepted : 2000.08.26
  • Published : 2000.09.20

Abstract

Stimulation of the auricle is known to be effective in reducing obesity. The aim of the present study is to investigate whether stimulating a specific auricular acupuncture point is effective on suppression of appetite. Cholesystokinin (CCK) is known to induce a powerful feeding response after central administration and particularly abundant in the cerebral cortex. In food-deprived rats exhibiting a strong drive for feeding, decreased CCK release was markedly detected in the cerebral cortex of the brain. Needling the fasted rats on the specific auricular region increased the CCK level of the cerebral cortex. In conclusion, stimulating the specific auricular points increases CCK-expression in the cerebral cortex of the fasted rats and may be useful for controlling obesity.

Keywords

Acknowledgement

Supported by : 한국학술진흥재단

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