한국식품저장유통학회지 (Food Science and Preservation)

  • 제7권1호
  • /
  • Pages.68-73
  • /
  • 2000
  • /
  • 3022-5477(pISSN)
  • /
  • 3022-5485(eISSN)
한국식품저장유통학회 (The Korean Society of Food Preservation)
권호 표지

감마선조사 생약재 (어성초, 구기자)의 안전성에 관한 유전독학성적 평가

Genotoxicological Safety of the Two gamma-Irradiated Herbs ; Houttuynia cordata Thunberg and Kycium Chinense Miller

  • 조성기 (한국원자력연구소 방사선식품.생명공학기술개발팀) ;
  • 유영법 (한국원자력연구소 방사선식품.생명공학기술개발팀) ;
  • 오헌 (한국원자력연구소 방사선식품.생명공학기술개발팀) ;
  • 곽연길 (한국원자력연구소 방사선식품.생명공학기술개발팀) ;
  • 변명우 (한국원자력연구소 방사선식품.생명공학기술개발팀)
  • Jo, Sung-Kee (Team for Radiation Food Technology and Bioscience Korea Atomic Energy Research Institute) ;
  • Yu, Young-Beob (Team for Radiation Food Technology and Bioscience Korea Atomic Energy Research Institute) ;
  • Oh, Heon (Team for Radiation Food Technology and Bioscience Korea Atomic Energy Research Institute) ;
  • Kwak, Youn-Gil (Team for Radiation Food Technology and Bioscience Korea Atomic Energy Research Institute) ;
  • Byun, Myung-Woo (Team for Radiation Food Technology and Bioscience Korea Atomic Energy Research Institute)
  • 발행 : 2000.03.01
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초록

These experiments were performed to investigate the safety of two herbs-Houttuynia cordata Thunberg and Lycium chinese Miller-irradiated with gamma-rays in respect of genotoxicity. Water extracts from the 10 kGy gamma-irradiated herbs were examined in two short -term in vitro tests ; (1) Salmonella typhimurium reversion assay (Ames test) in strain TA 98 and Ta100 and (2) Micronuclues test on clutured Chinese hamster ovary(CHO) cells. No mutagenicity was detected in the two assays with or without metabolic activation . From these results , the safety of the herbs irradiated with gamma-rays at practical doses could be revealed in further tests of genotoxicity in vivo, chronic and reproductive toxicity.

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