Journal of Nutrition and Health

The Korean Nutrition Society (한국영양학회)
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Effects of Korean Leek and Dietary Fat on Plasma Lipids and Platelet Aggregation in Hypercholesteroloemic Rats

부추와 식이지방이 고지혈증 흰쥐의 혈액성상 및 혈소판 응집에 미치는 영향

  • 홍서아 (대전대학교 식품영양학과)
  • Published : 2000.06.01
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Abstract

The purpose of the present study was to investigate the effect of Korea leek on plasm lipids and platelet aggregation in hypercholesterolemic rats fed different dietary fat. Sprague-Dawley rats were fed with hyperlipidemic diet for 4 weeks in order to induce hyperlipidemia, followed by the feeding of experimental diets for additonal 4 weeks. We used three kinds of lipid(perilla oil, corn oil and lard). Korean leek of experimental diets was prepared by drying and milling. Powdered Cellulose and powdered Korean leek were added to experimental diets at the level of 5% (w/w). Serum concentrations of total lipid, total triglyceride, total cholesterol and LDL-cholesterol decreased in the order of perilla oil, corn oil and lard. Korean leek significantly decreased total lipid, total cholesterol, LDL-cholesterol, platelet count, prothrombin time, and platelet aggregation in rats fed a lard diet. The present observation indicates that Korean leek might be helpful for the prevention and threapy of hyperlipidemia and platelet aggregation.

Keywords

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