Effects of Cryosurgery of the Third Eyelid Gland on Tear Production and Histological Changes in Dogs

개에서 제3안검선 냉동수술이 눈물생산량 및 조직학적 변화에 미치는 영향

  • 서강문 (강원대학교 동물자원과학대학 수의학과) ;
  • 공인주 (강원대학교 동물자원과학대학 수의학과)
  • Published : 2000.06.01

Abstract

The effects of cryosurgery on tear production and histological changes of the third eyelid were studied in dogs. Clinically normal 12 mixed breeds weighing 2∼6 kg were divided into three groups and treated as follows; 45 seconds double freeze-thaw treated group, 60 seconds double freeze-thaw treated group and 90 seconds double freeze-thaw treated group. The significant decrease of the tear production after cryosurgery was shown in all groups throughout the observed periods(p<0.05). However, there was no difference among groups. The main complications after cryosurgery were chemosis and conjunctival injection. Other complications such as eyelid edema, eyelid depigmentation and keratitis were more preominent in group III compared to those of groups I and II. On histopathological examination, chronic inflammatory changes and regeneration of the third eyelid glands were noted in group I and predominated loss of the third eyelid glands and necrosis of hyaline cartilage were observed in group III However, such changes were less appeared in group II. The results of this study suggested that double freeze-thaw cryosurgery for 60 seconds on the third eyelid glands would be the most effective method for treating tear staining syndrome.

Keywords

References

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