Archives of Pharmacal Research
- Volume 23 Issue 5
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- Pages.450-454
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- 2000
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- 0253-6269(pISSN)
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- 1976-3786(eISSN)
Synthesis and in Vitro Cytotoxicity of 2-Alkylaminosubstituted Quinoline Derivatives
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Lee, Hee-soon
(College of Pharmacy, Chungbuk National University)
;
- Lee, Jee-man (College of Pharmacy, Chungbuk National University) ;
- Hong, Seoung-Soo (College of Pharmacy, Chungbuk National University) ;
- Sung-Il (College of Medicine, Kunkuk University) ;
- Jung, Sang-Hun (College of Pharmacy, Chungnam National University) ;
- Jahng, Yurng-dong (College of Pharmacy, Yeoungnam University) ;
- Cho, Jung-sook (College of Medicine, Dongguk University)
- Published : 2000.10.01
Abstract
Eight 2-alkylaminosubstituted 5,8-dimethoxy-4-methylquinolines and nine 2-alkylaminosub-stituted or 2,6-disubstituted 4-methylquinoline-5,8-diones were synthesized and evaluated in vitro cytotoxicity against four human cancer cell lines (HOP62, SK-OV-3, HCT15 and SF295).