YAKHAK HOEJI (약학회지)

The Pharmaceutical Society of Korea (대한약학회)
권호 표지

Effects of Some Sedative Oriental Medicines on Neurotransmission and Antioxidative System in vitro

신경안정 생약 추출몰이 in vitro에서 신경전달효소 및 항산화계에 미치는 영향

  • Park, Yong-Ki (College of Oriental Medicine, Dongguk University) ;
  • Kang, Byung-Soo (College of Oriental Medicine, Dongguk University) ;
  • Yun, En-Kyung (College of Oriental Medicine, Dongguk University) ;
  • Kang, So-Im (Department of Biochemistry. Dongguk University) ;
  • Park, Chang-Hun (Department of Biochemistry. Dongguk University) ;
  • Lee, Dong-Ung (Department of Biochemistry. Dongguk University) ;
  • Ha, Jeoung-Hee (Department of Pharmacology, College of Medicine, Yeungnam University) ;
  • Huh, Keun (College of Pharmacy, Yeungnam University)
  • Published : 2000.02.01
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Abstract

The extracts of Euphoria longan, Ziryphus jujuba, Thuja orientalis, Polygala tenuifolia, Acorus gramineus, Cyperus rotundus, Poria cocos, Uncaria rhynchophylla, and Albizzia julibrissin, which have been used as sedative drugs in Korean folk medicine, were evaluated for their effects on neurotransmission and antioxidative system in vitro. Among the tested drugs, Acorus gramineus showed most inhibitory activities on monoamine oxidase, xanthine oxidase, aldehyde oxidase, and lipid peroxidation and Uncaria rhynchophylla also inhibited most effectively GABA transaminase and DPPH radical.

Keywords

References

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