Clinical and Experimental Reproductive Medicine

The Korean Society for Reproductive Medicine (대한생식의학회)
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A Case of Recurrent Spontaneous Abortion Successfully Delivered by Using Preimplantation Genetic Diagnosis

착상전 유전진단을 이용하여 성공적으로 분만한 반복자연유산 1례

  • Nam, Yoon-Sung (Department of Obstetrics and Gynecology, College of Medicine, Pocheon CHA University) ;
  • Lee, Sook-Hwan (Department of Obstetrics and Gynecology, College of Medicine, Pocheon CHA University) ;
  • Oum, Ki-Bung (Department of Andrology, College of Medicine, Pocheon CHA University) ;
  • Lee, Eun-Jung (Department of Genetics, College of Medicine, Pocheon CHA University) ;
  • Chung, Hyung-Min (Department of Embryology, College of Medicine, Pocheon CHA University) ;
  • Cha, Kwang-Yul (Department of Obstetrics and Gynecology, College of Medicine, Pocheon CHA University)
  • 남윤성 (포천중문의과대학 산부인과학교실) ;
  • 이숙환 (포천중문의과대학 산부인과학교실) ;
  • 엄기붕 (포천중문의과대학 남성불임연구실) ;
  • 이은정 (포천중문의과대학 유전학연구실) ;
  • 정형민 (포천중문의과대학 체외수정연구실) ;
  • 차광열 (포천중문의과대학 산부인과학교실)
  • Published : 2000.09.30
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Abstract

Objective: To report the successful delivery in a patient of recurrent spontaneous abortion caused by chromosomal abnormality. Material and Method: Case report. Results: Twelve oocytes were obtained by in vitro fertilization. Of eleven oocytes fertilized, two embryos turned out to be normal by using fluorescent in situ hybridization on blastomere biopsy. The patient succeeded in pregnancy and the result of amniocentesis was found to be normal. She delivered the healthy female baby by cesarean section. Conclusions: The successful delivery is possible in recurrent spontaneous abortion related with reciprocal translocation by using preimplantation genetic diagnosis.

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