Journal of Acupuncture Research

Korean Acupuncture & Moxibustion Medicine Society (대한침구의학회)
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Scavenging Effect of Bee Venom for Acua-acupuncture against Nitric Oxide

봉독약침액의 Nitric Oxide에 대한 소거 효과

  • Published : 2001.12.20
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Abstract

목적 : 본 연구는 최근 임상에서 많이 사용하는 봉독약침액의 nitric oxide (NO)에 대한 소거효과를 분석하기 위하여 실행되었다. 방법 : 양성대조군으로 비타민과 실험군으로 국산 봉독과 미국산 봉독에 NO를 분비하는 S-nitroso-N-acetylpenicillamine (SNAP)을 투여한 후 NO의 농도를 540 nm 파장의 자외선 흡수량을 측정하여 평가하였다. 결과 : 국산 봉독은 $100{\mu}g/m{\ell}$에서 SNAP 처리 1.5, 3, 6 및 12시간에 대조군 (100%)과 비교하여 각각 $86.7{\pm}1.5,\;103.8{\pm}1.9,\;88.3{\pm}2.9$ 및 85.6{\pm}3.2%$의 잔류 NO 농도를 보였고, 1.5, 6 및 12시간에서 유의한 NO 소거 효과를 나타냈다. 미국산 봉독에서는 각각 $74.0{\pm}2.2,\;66.5{\pm}10.9,\;86.1{\pm}2.8$ 및 $59.1{\pm}3.8%$로 모든 시간에서 유의한 결과를 보였다. 결론 : 이상의 봉독의 NO 소거효과는 봉독 약침액이 임상에서 동통, 종창, 등에 치료에 사용하는 작용기전의 하나로 사료된다.

Keywords

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