Journal of Acupuncture Research

Korean Acupuncture & Moxibustion Medicine Society (대한침구의학회)
권호 표지

Effects of Chaenomelis fructus Herbal Acupuncture on Muscle Fiber in Muscle Atrophy Rat induced by Hindkimb Suspension

목과약침(木瓜藥鍼)이 후지체공(後肢滯空)으로 유발(誘發)된 근위축(筋萎縮) 흰쥐의 근섬유(筋纖維) 변화(變化)에 미치는 영향(影響)

  • Chun, Chul-Ki (Department of Acupuncture & Moxibustion, College of Oriental Medicine, Kyung-Hee University) ;
  • Nam, Sang-Soo (Department of Acupuncture & Moxibustion, College of Oriental Medicine, Kyung-Hee University) ;
  • Park, Dong-Suk (Department of Acupuncture & Moxibustion, College of Oriental Medicine, Kyung-Hee University)
  • 전철기 (경희대학교 한의과대학 침구학교실) ;
  • 남상수 (경희대학교 한의과대학 침구학교실) ;
  • 박동석 (경희대학교 한의과대학 침구학교실)
  • Received : 2001.01.06
  • Accepted : 2001.01.15
  • Published : 2001.02.20
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Abstract

Objective : This experimental study was designed to investigate the effect of Chaenomelis fructus herbal acupuncture on the soleus muscle and tibialis anterior muscle of hindlimb-suspended rats. The measurement have been performed on the composition of type I, type IIa and type IIb muscle fibers in the soleus muscle and tibialis anterior muscie - histochemical study. Materials and Methods : Sprague-Dawley rats weighing about 250g were subjected to hindlimb suspension and divided into six groups; 1. Normal group: normai group 2. Control group: group of hindlimb suspension for 7 days 3. NT group: non-treatment group for 2 or 4 weeks after 7days of hindlimb suspension. 4. EX gtoup: running exercise group for 2 or 4 weeks after 7days of hindlimb suspension. 5. HA group: administration of Chaenomelis fructus herbal acupuncture during 2 or 4 weeks after 7 days of hindlimb suspension. 6. EXHA group: administration of Chaenomelis fructus herbal acupuncture and running exercise during 2 or 4 weeks after 7 days of hindlimb suspension. Results Results : 1. The composition of type I muscle fibers in the soleus muscle significantly increased in 2 or 4 weeks HA and EXHA groups more than control group, and the composition of type IIa muscle fibers in the soleus muscle significantly decreased in 2 or 4 weeks HA and EXHA goups more than control group. 2. The composition of type I muscie fibers in the tibialis anterior muscle significantly increased in 2 or 4 weeks HA and EXHA groups more than control group, and the composition of type IIb muscle fibers in the soleus muscle significantly decreased in 2 or 4 weeks HA and EXHA groups more than control group. 3. The size of type I muscle fibers in the soleus muscle significantly increased in 2 or 4 weeks HA and EXHA groups more than control group, and the size of type IIa muscle fibers in the soleus muscle significantly increased in 2 weeks EXHA group and 4 weeks HA and EXHA groups more than control group. 4. The size of type I, IIa muscle fibers in the tibialis anterior muscle significantly increased in 2 or 4weeks HA, EXHA and EX groups more than control group, and the size of type IIb muscle fibers significantly increased in 2 weeks EXHA group and 4 weeks HA, EXHA and EX groups more than control group. 5. The capiliaries number per fiber of muscle fibers in the soleus and tibialis anterior muscle showed no differences in all experimental groups more than control group. Conclusion : According to the above results, it is shown that Chaenomelis fructus herbal acupuncture could be effective in the treatment of muscle atrophy.

Keywords

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