Effect of Meristotheca papulosa on Lipid Concentration of Serum and Liver in Rats Fed High Fat Diet

해조류 갈래곰보가 고지방 식이를 급여한 흰쥐의 혈액 및 간장 지질 농도에 미치는 영향

  • 박희연 (국립수산진흥원 남해수산연구소) ;
  • 윤호동 (국립수산진흥원 남해수산연구소) ;
  • 오은경 (국립수산진흥원 남해수산연구소)
  • Published : 2001.02.01

Abstract

This study was carried out to investigate the effect of Meristotheca papulosa on lipid concentration of serum and liver in rats fed high fat diet for 4 weeks. Experimental groups ere divided into normal group (5% corn oil), high fat diet group (5% corn oil+20% lard), high fat diet and 5% or 10% Meristotheca papulosa treated group. The weights of kidney, heart and tests were not significantly different among the group, but weight of liver was significantly decreased by supplement of Meristotheca papulosa (10%). The contents of serum total lipid, trigly-ceride, total cholesterol, free cholesterol, cholesterol ester and atherogenic index were decreased, while HDL-cholesterol was increased by Meristotheca papulosa supplementation compared to high fat diet group. Meristotheca papulosa supplement has obvious effects on lowering hepatic total lipid, triglyceride and total cholesterol. Our findings suggest that Meristotheca papulosa supplement can improve lipid metabolism in high fat fed rats.

Keywords

References

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