A Study of Body Anthropometry and Dietary Factors Affecting Bone Mineral Density in Korean Pre- and Postmenopausal Women

우리나라 일부 폐경전.후 여성의 골밀도와 그에 영향을 미치는 체형 및 식이인자에 관한 연구

  • 승정자 (숙명여자대학교 식품영양학과) ;
  • 백수경 (숙명여자대학교 식품영양학과) ;
  • 이행신 (한국보건산업진흥원 식품산업단) ;
  • 김미현 (숙명여자대학교 식품영양학과) ;
  • 최선혜 (숙명여자대학교 식품영양학과) ;
  • 이소연 (숙명여자대학교 식품영양학과) ;
  • 이다홍 (숙명여자대학교 식품영양학과)
  • Published : 2001.02.01

Abstract

The objective of this study is to examine the factors affecting bone mineral density in pre- and postmenopausal women. The subject were 30 Korean premenopausal women with mean ages of 33.6 years, and 30 Korean post menopausal women with mean ages of 63.3 years without diagnosed diseases. Data for food and nutrient intake were obtained by the24-hour recall method. BMD of lumbar spine and femoral neck were measured by the dual-energy X-ray absorptiometry (DEXA). Anthropometric measurement were made, and a blood sample was taken for assay osteocalcin. The results are summarized as follows: 16.67% of the subjects in the premenopausal women and 87.33% of the subjects in the postmenopausal women was less than the korean RDA level exceping phosphorus and vitamin C. In the premenopausal women, BMD of lumbar spine is correlated significantly with anthropometric measurement such as weight, waist circumference, BMI, and body fat mass BMD of femoral neck for the premenopausal women is correlated significantly with weight, BMI, waist circumference, body fat mass, hip circumference, and BMDs of both site are negatively correlated with lean body mass, total body water, but they are not related with intake of nutrients in this study. In the postmenopausal women group, BMDs of both site are not significantly correlated with anthropometric measurement, but BMD of lumbar spine showed positive relation with intake of energy, protein, and carbohydrate. In conclusion, adequate nutrient intake, especially energy, protein have been suggested to prevent the loss of bone mineral density in the postmenopausal women. Also, adequate body weight and BMI have been suggested in the premenopausal women.

Keywords

References

  1. J. Nutr. v.116 NIH consensus conference;osteoporosis,factors contributing to osteoporosis Spencer H.;Kramer L.
  2. Clin. Orthop. v.165 On aging bone loss Mazess R. B.
  3. Korean J. Nutr. v.29 The effect of nutrient intake and energy expenditure on bone mineral density of korean women in Taegu Lee H. J.;Choi M. J.
  4. Calcif. Tissue Int. v.66 Lifestyle determination of bone mineral;a comparison between prepubertal Asian- and Caucasian-Canadian boys and girls McKay H. A.;Petit M. A.;Khan K. M.;Schutz R. W.
  5. Am J. Clin. Nutr. v.65 Nutritional influences on bone mineral density;a crosssectional study in premenopausal women New S. A.;Bolton-smith C;Grubb D. A.;Reid D. M.
  6. Maturitas v.27 The effect of body composition on bone density in pre- and posemenopausal women Douchi T.;Oki T.;Nakamura S.;Ijuin H.;Yamamoto S.;Nagata Y.
  7. Am. J. Clin. Nutr. v.53 Bone density in premenopausal women;effect of age,dietary intake,physical activity,smoking and birth-controll pills Mazess R. B.;Barden H. S.
  8. Osteoporos. Int. v.8 Cigarette smoking, alcohol and caffeine consumption and bone mineral density in postmenopausal women;the Nottingham EPIC study group Graige M. J.;Coupland C .A.;Cliffe S. J.;Chivers C. E.;Hosking D. J.
  9. Calcif. Tissue. Int. v.64 Cross-sectional study of weight-bearing activity on proximal femur bone mineral density Mayoux-Benhamou M. A.;Leyge J. F.;Roux C.;Revel M.
  10. Endocr. J. v.41 Physical exercise increase bone mineral density in postmenopausal women Shimegi S.;Yanagita M.;Okano H.;Yamada M.;Fukui H.;Fukumura Y.;Ijuki Y.;Kojima I.
  11. Maturitas v.9 Adrenal androgens, sex-hormone binding globulin and bone density in osteroporotic menopausal women;is there a relationship? Wild R. A.;Buchanan J, R,;Myers C.;Lloyd T.;Demers L. M.
  12. Korean J. Nutr. v.29 Influencing factors on the bone status of rural menopausal women Choi E. J.;Lee H. O.
  13. J. Korean Soc. Food Sci. Nutr. v.27 Bone densities of the middle aged women residing in the city and related factors-2.Study on the factors affecting bone densities of middle aged women Son S. M.;Lee Y. N.
  14. Adv. Nutr. Res. v.9 The gain and loss of bone in the human lifecycle Aloia J. F.
  15. Am. J. Clin. Nutr. v.54 Influence of calcium intake and growth indexes on vertebral bone mineral density in young females Sentipal J. M.;Wardlaw G. M.;Mahan J.;Matkovic V.
  16. J. Bone Miner. Res. v.14 Dietary calcium and bone density in adolescent girls and young women in Europe Kardunal A. F.;Ando S.;Chaeles P.;CharzeWska J.;Rotily M.;Vaananen K.;Van Erp-Baart A. M.;Heikkinen J.;Thomsen J.;Maggiolini M.;Deloraine A.;Chabros E.;Juvin R.;Schaafsna G.
  17. J. Clin. Endicrino. Metab. v.84 Changes in bone turnover in young women consuming different lrvels of dietary protein Kerstetter J. E.;Mitnick M. E.;Gundberg C. M.;Caseria D. M.;Ellison A. F.;Carpenter T. O.;Insogna K. L.
  18. Calcif. Tissue Int. v.58 Dietary protein intake and bones mass in women Cooper C.;Atkinson E. J.;Hensrub D.;Wahner H. W.;O'Fallon W. M.;Riggs B. L.;Melton 3rd L. J.
  19. Korean J. Nutr. v.29 Effects of dietary calcium.protein,and Phodphorus intakes on bone mineral density in korean Premenopausal women Oh J. J.;Hong E. S.;Baik I. K.;Lee H. S.;Lim H. S.
  20. Calcif. Tissue Int. v.67 Bone mass and markers of bone and calcium metabolism in postmenopausal womwn treated with 1,25-dihydroxy-vitamin D(calcitrol)for four years Sairanen S.;Karkkainen M.;Tahtela R.;Laitinen K.;Makela P.;Lamberg-Allardt C.;Valimaki M. J.
  21. Calcif. Tissue. Int. v.67 The relationship of dietary vitamin C intake to bone mineral density;results from the PEPI study Hall S. L.;Greendale G. A.
  22. J. Bone Miner. Res. v.15 Vitamin K₂(menatetrenone)effectively prevents fractures and sustains lumbar bone mineral density in osteoporosis Shiraki M.;Shiraki Y.;Aoki C.;Miura M.
  23. Ann. Intern. Med. v.129 Excessive dietary intake of vitamin A is associated with reduced bone mineral density and increased risk for hip fracture Melhus H.;Michaelsson K.;Kinfmark A.;Bergstrom R.;Holmberg L.;Mallmin H.;Wolk A.;Ljunghall S.
  24. Am. J. Clin. Nutr. v.69 Postassium, magnessium, and fruit and vegetable intakes are associated with greater bone mineral density in elderly men and women Tucker K. L.;Hannan M. T.;Chen H.;Cupples L. A.;Wilson P. W.;Kiel D. P.
  25. Am J. Clin. Nutr. v.69 Prospective study of dietary protein intake and risk of hip fracture in postmenopausal women Munger R. G.;Cerhan J. R.;Chiu B. C.-H
  26. J. Nutr. v.128 Excess dietary protein can adversely affect bone Barzel U. S.;Massey L. K.
  27. J. Nutr. v.125 Orally dosed genistein from soy and prevention of cancellous bone loss in two ovariectomised rat models Anderson J. J.;Ambrose W. W.;Garner S. C.
  28. Am. J. Clin. Nutr. v.68 no.SUP.1 Soy protein and isoflavones;their effects on blood lipids and bone density in postmenopausal women Potter S. M.;Baum J. A.;Teng H.;Stillman R. J.;shay N. F.;Erdman Jr. J. W.
  29. Am. J. Clin. Nutr. v.68 no.SUP.1 Role of soy protein with normal or reduced isoflavone content in reversing bone loss induced by ovarian hormone defiency in rat Arjmandi B. H.;Getlinger M. J.;Goyal N. V.;Alekel L.;Hasler C. M.;Juma S.;Drum M. L.;Holis B. W.;Kukreja S. C.
  30. Am. J. Clin. Nutr. v.68 no.SUP.1 Phytoestrogens the biochemistry, physiology and implication for human health of soy isoflavones Setchell K.
  31. 98 NAtional nutrition survey report Minisry of health and welfare
  32. 70 National nutrition survey report Minisry of health and welfare
  33. Korean J. Nutr. v.32 Some factors affecting bone mineral density of Korean rural women Lee J. S.;Yu C. H.
  34. Arch. Intern. Med. v.22 Effects of tamoxifen on lumbar spine bone mineral density in postmenopausal women after 5 year Love R. R.;Barden H. S.;Mazess R. B.;Epstein S.;Chappel R. J.
  35. 식품성분표(5차 개정판) 농촌진흥청 농촌생활연구소
  36. Food composition and nutrient tables Souci S. W.
  37. 食品微量元素含量表(第1出版) 鈴木表夫
  38. J. Chromatogr. B. v.662 High-performance liquid chromatography assay of isoflavonoids and coumesterol from human urine Franke A. A.;Custer L. J.
  39. Korean J. Nutr. v.33 A study on the factors affecting bone mineral density in adult women-based on the mothers of the elementary school students Kim K. R.;Kim. K. H.;Lee E. K.;Lee. S. S.
  40. J. Kor. Soc. Endocrinol. v.11 Estrogen receptor gene polymorphism, urinary estrogen metabolites and bone mineral density in Korean postmenopausal women Lee J. H.;Lim S. K.;Won Y. J.;Kwon S. H.;Cha B. S.;Song Y. D.;Lee H. C.;Hu K. B.;Jung B. C.
  41. 건강의학 통계연보 v.3 아산재단 서울중앙병원 건강증진센터
  42. Korean J. Community Nutrition v.5 A study on dietary isoflavone intake from soy foods and urinary isoflavone execretion and menopausal symptoms in Korean women in rural areas Sung C. J.;Choi S. H.;Kim M. H.;Park M. H.;Ko B. S.;Kim H. K.
  43. J. Korean Soc. Food Sci. Nutr. v.29 Estimated isoflavone intake from soy products in Korean middle-aged women Lee S. K.;Lee M. J.;Yoon S.;Kwon D. J.
  44. Am. J. Clin. Nutr. v.60 Biological effects of a diet of soy protein rich in isoflavones on the menstrual cycle of premenopausal women Cassidy A.;Bingham S.;Setchell K. D.;
  45. Menopause v.6 Effect of soy protein supplementation on serum lipoproteins blood pressure and menopausal symptoms in premenopausal women Washburn S.;Burke G. L.;Morgan T.;Anthony M.
  46. Am. J. Clin. Nutr. v.72 Isoflavone-rich soy protein isolate attenuates bone loss in the lumbar spine of perimenopausal women Alekel D. L. A.;Germain A. St.;Peterson C. T.;Hanson K. B.;Stewart J. W.;Toda T.
  47. Ann. Med. v.29 Phyto-oestrogens and western disease Adlercreutz H.;Mazur W.
  48. Korean J. Nutr. v.19 The nutrition and health survey of aged people in a rural area-1. The relationship between the food habit and the health responses to the todai health index Cho Y. S.;Lim H. S.
  49. J. Nutr. v.123 Dietary phodphorus calcium metabolism and bone Calvo M. S.
  50. Korean J. Nutr. v.31 Some factors affecting bone density of Korean college women Yu C. H.;Lee Y. S.;Lee J. S.
  51. J. Bone. Miner. Res. v.12 Determinants of peak bone mass in Chinese women aged 21~40 years Ⅲ. Physical activity and bone mineral density Ho S. C.;Wong E.;Chan S. G.;Lau J.;Chan C.;Leung P. C.
  52. Korean J. Nutr. v.31 The relationship between food habit, nutrient intakes and bone mineral density and bone mineral content in adult women Choi M. J.;Chung Y. J.
  53. Ph.D. Dissertation A study on bone metabolism and urinary isoflavones concentration associated with dietary intake of soybean and soy products in Korean postmenopausal women Choi S. H.;
  54. J. Gerontol. A Biol. Sci. Med. Sci. v.52 Bone mineral density and biochemical markers of bone turnover in healthy elderly men and women Krall E. A.;Dawson-Hughes B.;Hirst K.;Gallagher J. C.;Sherman S. S.;Dalsky G.
  55. J. Nutr. v.110 Studies on the metabolism of protein-induced hypercalciuria in older man and women Schuette S. A.;Zernel M. B.;Linkswiler H. M.
  56. Am. J. Clin. Nutr. v.71 Dietary influences on bone mass and bone metabolism;further evidence of a positive link between fruit and vegetable consumption and bone health? New S. A.;Robins S. P.;Campbell M. K.;Martin J. C.;Garton M. J.;Bolton-Smith C.;Grubb D.A.;Lee S. J.;Reid D. M.
  57. Am. J. Clin. Nutr. v.68 Dietary calcium, protein and phodphorus are related to bone mineral density and content in young women Teegarden D.;Lyle R. M.;McCabe G. P.;McCabe L. D.;Proulx W. P.;Michon K.;Knight A. P.;Jhonston C. C.;Weaver C. M.
  58. N. Engl. J. Med. v.330 Improved mineral balance and skeletal metabolism in postmenopausal women treated with potassium bicarbonate Sebastian A.;Harris S. T.;Ottawa J. H.;Todd K. M.;Morris R. C.