Journal of the Society of Cosmetic Scientists of Korea (대한화장품학회지)
- Volume 27 Issue 1
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- Pages.29-42
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- 2001
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- 1226-2587(pISSN)
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- 2288-9507(eISSN)
In Vivo Evaluation of Multi Lamellar Vesicle Liposome’s Percutaneous Absorption and Stability
- Joung, Min-Seok (Hankook Cosmetics R&D Center, Pucheon City) ;
- Park, Jong-Oan (Hankook Cosmetics R&D Center, Pucheon City) ;
- Seo, Bong-Seok (Hankook Cosmetics R&D Center, Pucheon City) ;
- Ryu, Chang-Duck (Hankook Cosmetics R&D Center, Pucheon City)
- Published : 2001.09.01
Abstract
We had prepared MLV liposome with Hibiscus Esculentus Ext.(HEE) which have fluorescent light in order to evaluate its percutaneous absorption about hairless rat skin. Then we investigated particle size of MLV using confocal laser scanning microscope(CLSM) and transmission electron microscope(TEM), respectively. Stability of MLV liposome and penetration of MLV liposome to hairless rat skin was measured by CLSM. As a result of experiments, MLV was globular shape and the rage of particle size was 0.3-0.5
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