Antimicrobial Activities of (-)Epicatechin from Ulmus davidiana var. japonica Cortex

  • Lee, Gyu-Hee (Department of Food Science and Technology, Chungnam National University) ;
  • Shim, Chang-Ju (Department of Food Science and Technology, Chungnam National University) ;
  • Chang, Yeong-Il (Department of Food Science and Technology, Chungnam National University) ;
  • Park, Seong-Hyun (Department of Food Science and Technology, Chungnam National University) ;
  • Oh, Hong-Rock (Division of Animal Science and Resoures, Chungnam National University) ;
  • Oh, Man-Jin (Department of Food Science and Technology, Chungnam National University)
  • Published : 2001.12.01

Abstract

The extract of Ulmus davidiana var. japonica cortex has known as natural anti-inflammatory substance in East Asia. For the identification of antimicrobial substance, it was extracted by using methanol and fractionated by using different organic solvents. The fraction of butanol was represented the highest antimicrobial activities. Therefore, the butanol fraction was purified and identified the chemical structure by $^1$H and $^{13}$ C-NMR spectra, FT-IR and EI/MS spectroscopies. The isolated antimicrobial substance was identified as cis-2-[3,4-dihydroxy phenyl]-3,4-dihydro-2H-1-benzopyran-3,5,7-triol, which has commonly known as (-)epicatechin. Its minimum inhibitory concentrations (MICs) against Staphylococcus aureus and Listeria monocytogenes were shown as 100 $\mu\textrm{g}$/mL, respectively.

Keywords

References

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