YAKHAK HOEJI (약학회지)

The Pharmaceutical Society of Korea (대한약학회)
권호 표지

Preliminary Toxicity and General Pharmacology of KML-IIU, a Purified pectin from Korean Mistletoe (Viscum album coloratum)

한국산 겨우살이 (Viscum album coloratum)로부터 정제된 렉틴 성분 KML-IIU의 예비 독성 및 일반 약리 시험

  • 강태봉 (한동대학교 생물식품공학부) ;
  • 윤택준 (경희대학교 동서의학대학원 종양연구팀) ;
  • 김종배 (한동대학교 생물식품공학부) ;
  • 송성규 (한동대학교 생물식품공학부) ;
  • 이관희 (한동대학교 생물식품공학부)
  • Published : 2001.06.01
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Abstract

The study was carried out to evaluate the preliminary toxicity and general pharmacology of KML-IIU, a purified pectin from Korean Mistletoe (Viscum album coloratum). KML-IIU was administered intravenously to ICR mice and Spargue-Dawley rats to investigate the acute toxicity. LD50 values in mice and rats were above 30 $\mu$g/kg. KML-IIU had no effects on the general behaviors, acetic acid induced writhing syndrome, pentobarbial induced sleeping time, pentylenetetrazole induced convulsion and the change of body temperature. In addition, KML-IIU did not show any effects on digestive system and blood coagulation system.

Keywords

References

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