Effects of Low Power Laser Irradiation on the Spinal Cord for the Functional Regeneration of Crushed Sciatic Nerve in Rats

흰쥐 좌골신경 압좌손상 후 척수분절의 저강도 레이저 조사가 운동기능 회복에 미치는 영향

  • Kim, Souk-Boum (Major in Physical Therapy, Dept. of Rehabilitation Science, Graduate School, Targu University) ;
  • Kim, Dong-Hyun (Major in Physical Therapy, Graduate School of Rehabilitation Science, Taegu University) ;
  • Song, Ju-Min (Department of Physical Therapy, Division of Health Science, Taegu University) ;
  • Nam, Ki-Won (Department of Physical Therapy, Division of Health Science, Taegu University) ;
  • Kwon, Young-Shil (Lab. of Nerve regeneration, Department of Physical Therapy, College of Rehabilitation, Taegu University) ;
  • Kim, Jin-Sang (Department of Physical Therapy, College of Rehabilitation Science, Tagu University)
  • 김석범 (대구대학교 대학원 재활과학과 물리치료) ;
  • 김동현 (대구대학교 재활과학대학원 물리치료) ;
  • 송주민 (대구대학교대학원 재활과학과 물리치료) ;
  • 남기원 (대구대학교대학원 재활과학과 물리치료) ;
  • 권영실 (대구대학교 재활과학대학 물리치료학과 신경재생실) ;
  • 김진상 (대구대학교 재활과학대학 물리치료학과)
  • Published : 2001.12.21

Abstract

The purpose of the present study was to examine the functional recovery of the crushed sciatic nerve of rats after low-power laser irradiation applied to the corresponding segments of the spinal cord. After a crushed injury on the left sciatic nerve in rats. low-power laser irradiation was applied transcutaneously to corresponding segments of the spinal cord immediately after suture the wound by using 2000 mW, 2000Hz, 830 nm CaAIAs(Gallium-aluminum-arsenide) semiconductor diode laser. The laser treatment was performed with 10 minutes daily for 4 successive weeks. Functional recovery was evaluated per weekly following injury by sciatic function index(SFI),using data obtained by walking track analysis. For four weeks after crush injury, experimental group had significantly greater functional improvement than control group(${\alpha}$=0.05). In a experimental group, SFI was significantly increased for three weeks, but control group not increased for two weeks. This study suggests that low-power laser irradiation applied directly to the spinal cord can improve functional recovery of the crushed sciatic nerve in rats.

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