발달중인 Mongolian gerbil의 전뇌에서 TH 면역반응세포의 분포에 관한 연구

The study on the TH(tyrosine hydroxylase) immunoreactive cells in forebrain of developing mongolian gerbil

  • Lee, Kyoung-youl (College of Veterinary Medicine, Chungnam National University) ;
  • park, Il-kwon (College of Veterinary Medicine, Chungnam National University) ;
  • Kwon, Hyo-jung (College of Veterinary Medicine, Chungnam National University) ;
  • Park, Mi-sun (College of Veterinary Medicine, Chungnam National University) ;
  • Song, Chi-won (College of Veterinary Medicine, Chungnam National University) ;
  • Kim, Moo-kang (College of Veterinary Medicine, Chungnam National University) ;
  • Chang, Kyu-tae (Korea Research Institute of Bioscience & Biotechnology) ;
  • Lee, Kang-iee (College of Oriental Medicine, Taejon University) ;
  • Kim, Won-sik (College of Medicine, Chungnam National University) ;
  • Park, Won-hark (Department of Biology, Yeungnam University)
  • 심사 : 2001.05.28
  • 발행 : 2001.06.25

초록

The immunocytochemical localization of tyrosine hydroxylase(TH) is examined in the developmental forebrain of mongolian gerbil in order to determine changes in the distribution and cytology of neurons. At each of the different developmental stage, including prenatal(E)14, E16, E18, E20, postnatal(P)0, P2, P4 days, mongolian gerbils were sacrificed. In E14, TH-IR cells were predominantly round or oval in shape and their processes were very short. In olfactory blub, TH-IR cells were begun to appear from E20. In the striatum, we observed only fibers of TH-IR at all ages. From E16, TH-IR perikarya and fiber were present in periventricular nucleus and paraventricular nucleus of hypothalamus. The changes from the early to the late prenatal stages of development appear to be the result of an increase in number of TH-IR perikarya and processes. These results were shown slight differences to other rodents.

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