전자공학회논문지SC (Journal of the Institute of Electronics Engineers of Korea SC)

대한전자공학회 (The Institute of Electronics and Information Engineers)
권호 표지

다채널 LAPS용 pH 변화량 검출을 위한 적분 방식의 알고리듬 제안

Algorithm for Integral Method for Photocurrent Measurement of pH Variations Using Multichannel LAPS

  • 배상곤 (경북대학교 전자전기공학부) ;
  • 이승하 (경북대학교 전자전기공학부) ;
  • 강신원 (경북대학교 전자전기공학부) ;
  • 조진호 (경북대학교 전자전기공학부)
  • Bae, Sang-Kon (School of Electronic & Electrical Eng., Kyungpook National University) ;
  • Lee, Sung-Ha (School of Electronic & Electrical Eng., Kyungpook National University) ;
  • Kang, Shin-Won (School of Electronic & Electrical Eng., Kyungpook National University) ;
  • Cho, Jin-Ho (School of Electronic & Electrical Eng., Kyungpook National University)
  • 발행 : 2001.12.31
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초록

본 논문에서는 시간-농도 분해능을 필요로 하는 LAPS장치에 있어서, 광전류 특성 곡선의 변곡점을 찾아 이동량을 측정하는 대신에 특성 곡선의 적분값 변화를 이용하여 pH변화를 검출하는 방식을 제안하였다. 제안된 방식의 성능 확인을 위하여 시뮬레이션을 수행하였으며, 이로부터 약 80배의 감도 및 1000배의 분해능 증가를 확인하였다. 수행된 결과를 바탕으로 측정 시스템 및 2-0.03125 [mg/ml]농도의 효소가 묻은 스트립을 제작하여 측정한 결과, 동일한 샘플수에 대해 기존의 3.79-0.27[pH/min]보다 더 높은 3.76-0.08 [pH/min]의 pH변화감도를 측정할 수 있었다.

We proposed the detection method of pH variations by integrating a photocurrent characteristic curve, instead of finding an inflection point by differentiating it in LAPS system. By a simulation of the performance of the proposed method, we verified that it had 80 and 1000 times higher sensitivity and resolution than a conventional method. Then, with the implemented system based on the simulation results, we measured a pH variation which was given rise to a potential change on the LAPS surface exposed to 2-0.03125[mg/ml] enzyme solutions. As results, we observed that the proposed method has a higher sensitivity and resolution of 3.76-0.08[pH/min] pH variations than 3.79-0.27[pH/min] for conventional method with same samples.

키워드

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