한국식생활문화학회지 (Journal of the Korean Society of Food Culture)

  • 제17권1호
  • /
  • Pages.64-69
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  • 2002
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  • 1225-7060(pISSN)
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  • 2288-7148(eISSN)
한국식생활문화학회 (Korean Society of Food Culture)
권호 표지

서목태(Rhynchosia nulubilis) 추출물이 고지방 및 고콜레스테롤 식이 급여 흰쥐의 혈청 지질 농도에 미치는 영향

Effects of Methanol Extracts from Rhynchosia nulubilis on serum Lipid Concentrations in Rats fed High Fat and High Cholesterol Diet

  • 한성희 (원광보건대학 식품과학과) ;
  • 신미경 (원광대학교 생활과학대학 식품영양학과)
  • Han, Sung-Hee (Dept. of Food Science Wonkwang Health Science College) ;
  • Shin, Mee-Kyung (Dept. of Food of Nutrition, College of Human Environmental Science, Wonkwang University)
  • 발행 : 2002.02.28
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초록

The effects of the Rhynchosia nulubilis extracts on serum lipid concentrations were evaluated in rats. Forty-two male Sprague-Dawley rats weighing $100{\pm}10g$ were divided into six groups and fed high fat and high cholesterol diets for four weeks. Experimental groups were administered with following diets; basal fat diet(control) and basal and high fat diets with 1% cholesterol and Rhynchosia nulubilis extract(40mg/kg, 400mg/kg and 4000mg/kg). The concentrations of serum triglyceride in rats fed the Rhynchosis mulubilis extract, high fat, 1% cholesterol, and RN-HFC(-40, -400, -4000mg/kg) groups were lower than those in other groups. The concentrations of total cholesterol in the RN-HFC (-40, -400, -4000mg/kg) groups were lower than those in fat diet groups. The concentrations of HDL-cholesterol in serum of the RN-HFC(-40, -400, 4000mg/kg) groups were significantly higer than those of other groups. The levels of LDL-cholesterol in serum of the RN-HFC(-40, -400, -4000mg/kg) groups were tended to be lower than those of other groups. These results suggest that Rhynchosia nulubilis extract may reduce elevated levels of serum lipid concentrations in rats fed high fat diets.

키워드

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