Effects of Onsinhwan on the ovulation in rats

온신환(溫腎丸)이 백서(白鼠)의 배란(排卵)에 미치는 영향(影響)

  • Wee, Suk (Department of Oriental Obstetric and Gynecology, college of Oriental Medicine, Wonkwang University) ;
  • Min, Gyung-Hun (Department of Oriental Obstetric and Gynecology, college of Oriental Medicine, Wonkwang University) ;
  • Cho, Han-Baek (Department of Oriental Obstetric and Gynecology, college of Oriental Medicine, Wonkwang University) ;
  • Yoo, Sim-Keun (Department of Oriental Obstetric and Gynecology, college of Oriental Medicine, Wonkwang University) ;
  • Kim, Duck-Nim (Department of Oriental Obstetric and Gynecology, college of Oriental Medicine, Wonkwang University)
  • 위석 (원광대학교 한의과대학 부인과학 교실) ;
  • 민경헌 (원광대학교 한의과대학 부인과학 교실) ;
  • 조한백 (원광대학교 한의과대학 부인과학 교실) ;
  • 유심근 (원광대학교 한의과대학 부인과학 교실) ;
  • 김덕님 (원광대학교 한의과대학 부인과학 교실)
  • Published : 2002.11.30

Abstract

Onsinhwan(OSH : 溫腎丸) is used in female infertility, especially due to lack of kidney yang or Sinyanghe(腎陽虛). An attempt was made to evaluate the influences of OSH on the serum concentrations of FSH and LH, Estrogen, Progesterone and the histological and optical changes of ovary, ovary weight of rats. The results of the study were as follows : 1. Blood FSH level increased in experimental group as compared with control group on 7th day and 14th day, which showed no efficacy. 2. Blood LH level decreased in experimental group as compared with control group on 14th day, which showed no efficacy. 3. Blood Estrogen level increased in experimental group as compared with control group on 7th day and 14th day, which showed no efficacy. 4. Blood Progesterone level decreased in experimental group as compared with control group on 7th day and 14th day, which showed no efficacy. 5. In histological observations of ovary, ovulation increased in experimental group as compared control group on 7th and on 14th day, which showed no efficacy. 6. In optically observations of ovary, size and weight of ovary increased in experimental group on 7th day and on 14th day, which showed no efficacy. According to these results, OSH did not influence on the ovulation of ovary in rats.

Keywords

References

  1. 編註醫學入門 (外集) 李전
  2. 驗方${\cdot}$新法治百病叢書婦人病 鄭利巖;梁學林
  3. 육麟珠가 白鼠의 排卵과 卵巢에 미치는 影響 崔相淳
  4. 申氏本草學 申佶求
  5. 東醫寶鑑(雜病10卷) v.10 許浚
  6. 實用中西醫結合診斷治療學(上.下) 陳貴廷;楊思澍
  7. 東洋醫學大辭典 謝觀
  8. 再編集 東醫學辭典 科學百科辭典 綜合出版社
  9. 中醫處方大辭典 10卷 彭懷仁
  10. 新編中醫學敎材${\cdot}$婦産科學 上海中醫學院
  11. 婦科常見病實用方 柳長華
  12. 中醫綱目 徐學敏
  13. 中醫婦科學 羅元愷
  14. 中醫臨床婦科學 夏桂成
  15. 標準韓方婦人科 李鍾華;朴炳烈
  16. 부인과학 대한산부인과학회
  17. 임상부인과 내분비학 구병삼
  18. 王叔和脈經 王叔和
  19. 備急千金要方 孫思邈
  20. 새임상 부인과학 최유덕
  21. HARRISON'S 내과학 Isselbacher, Kurt J.
  22. 臨床內分泌學 閔獻基
  23. 韓方婦人科學 宋炳基
  24. 中西醫臨床婦科學 洪家鐵
  25. 不孕不育與月經周期調理 夏桂成
  26. 濟陰綱目 武之望
  27. 葉天士女科 葉桂
  28. 傳靑主男女科 傳山
  29. 大韓韓方婦人科學會誌 v.4 no.1 女性不姙의 原因分類에 關한 文獻的 考察 金哲源(등)
  30. 一百天學中醫婦科 戴德英;楊炳初
  31. 東醫臨床婦人科學(原 中醫臨床大全) 肖淑春
  32. 覆盆子 煎湯 投與에 의한 家兎의 子宮 및 卵巢 發育促進에 關한 硏究 尹鎭杓
  33. 香附子 煎湯 投與가 家兎의 卵巢에 미치는 影響 尹영根
  34. 調經種玉湯이 白鼠의 排卵에 미치는 影響 徐湧周
  35. 大韓韓方婦人科學會誌 v.8 開鬱種玉湯이 白鼠의 血中 卵胞刺戟 Hormone과 黃體化Hormone에 미치는 影響 金鍾桓
  36. 四製香附子가 白鼠 卵胞刺戟Hormone과 黃體化Hormone에 미치는 影響 尹鎭杓
  37. 加味調經散이 白鼠의 血中Hormone含量과 摘出子官筋에 미치는 影響 崔正順
  38. 黃帝內經素問譯解 楊維傑
  39. 諸病源候論 巢元方
  40. 東醫生理學 柳道坤
  41. 臨床本草學 辛民敎
  42. 인체생리학 고건일(등)
  43. Gynecology illustrated Mathew, G.;Colin, H.;Robin, C.
  44. Bailliers Clin. Endocr. Metabol. Opioid peptides in blood and cerebrospinal fluid during acute stress Owens, p.c.;Smith, R.
  45. 생리학 이병희
  46. Clin Endocrinol Metab v.7 Cyclic changes in antral fluid hormone concentrations in humans. McNatty, K.P.
  47. Obstet Gynecol v.69 Gonadotropin binding sites in human ovarian follicles & corpora lutea during the menstrual cycle Shima, K.;Kitayama, S.;Nakano, R.
  48. Fertil Steril v.38 The dominant ovarian follicle Hodgen, G.D.
  49. Fertil Steril v.38 The endocrinology of the menstrual cycle : in the interaction of folliclegenesis & neuroendocrine mechanisms Fritz, M.A.;Speroff, L.
  50. Clin Endocrinol Metab v.68 The importance of luteinizing hormone in the control of inhibin & progesterone secretion by the human corpus luteum McLachlan, R.I.;Cohen, N.L.;Vale, W.W.
  51. Am J Obstet Gynecol v.138 Temporal relationships between ovulation & defined changes in the concentration of plasma estradiol-17${\beta}$, luteinizing hormone, follicle-stimulating hormone & progesterone. I, prohibit Analysis World Health organization Task Force