Journal of Biomedical Engineering Research (대한의용생체공학회:의공학회지)

The Korean Society of Medical and Biological Engineering (대한의용생체공학회)
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Liquid Flow and Pressure Drop of an Outside Flow Membrane Oxygenator with Hollow Fibers

외부흐름 중공사 막형 인공폐의 액체흐름과 압력손실

  • 이삼철 (한려대하교 신소재공학과) ;
  • 김기범 (공과대학 화학공학부)
  • Published : 2002.02.01
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Abstract

The purpose of this study was to evacuate the effects of the number of tied hollow fibers in a novel membrane oxygenator that satisfied the limiting factor of minimizing the friction loss in the intravascular blood flow Pattern. The membrane oxygenator is a bundle consisted of several hundred ho1low fibers haying the outside diameter of 380 $\mu m$ and the axial jacket length of 600 mm. The eight different variation of tied hollow fibers in a bundle were designed. and the liquid flow pattern was controlled by a pump. The liquid pressure drop was measured by in vitro experiments using water and g1ycero1. Uniform blood flow pattern was observed for each number of tied hollow fibers. Pressure drop was 13-16 mmHg outside of the membrane oxygenator consisting of up to 700 ho1low fibers. More effective contact of liquid with the tied ho1low fibers was observed as a decrease in the number of the tied hollow fibers. and resulted in the enhancement of the friction tractor

본 연구에서는 혈관내 혈액 흐름의 압력손실을 최소화하여야 하는 제한 인자를 만족하는 새로운 막형 인공폐에서 액체흐름경향과 중공사 개수에 대한 압력손실 영향을 고찰하고자 하였다 막형 인공폐는 380 $\mu m$의 중공사 외경과 600 mm의 축 방향 길이를 갖는 수 백 개의 중공사로 이루어진 다발이다 중공사 다발은 8가지로 변화시켰으며 흐름은 펌프를 이용하여 조절하였다 혈액대용물질로 글리세롤 용액과 물을 사용하여 압력손실을 측정하였으며 동일한 흐름 경향을 각 중공사들에서 얻었다. 700개의 중공사로 이루어진 막형 인공 폐의 외부 압력손실은 13-16 mmHg이었으며 중공사 개수의 감소에 따른 마찰계수는 중공사와 액체와의 효과적인 접촉이 일어나므로 증가되었다.

Keywords

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