KSBB Journal

The Korean Society for Biotechnology and Bioengineering (한국생물공학회)
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Selective Adsorption of a Symmetrie Theophylline Imprinted Membrane Prepare by a Wet Phase Inversion Method

습식 상 전이법으로 제조된 Theophylline 각인 대칭 막의 선택적 흡착

  • 박중곤 (경북대학교 공과대학 화학공학과) ;
  • 오창엽 (경북대학교 공과대학 화학공학과) ;
  • 서정일 (경북대학교 공과대학 화학공학과)
  • Published : 2002.04.01
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Abstract

The theophylline imprinted membrane was prepared by a wet phase inversion method. Theophylline was implanted during copolymerization of acrylonitrile with acrylic acid or implanted in the dimethyl sulfoxide solution containing10 wt% copolymer, p(AN-co-AA). Rolling the glass plate, on which the copolymer solution was cast, in water removed the sponge layer and thus made the membrane symmetric. The adsorption selectivity of the membrane toward template molecule was increased with the coagulation temperature of the membrane and the initial concentration of the theophylline and caffeine mixture.

습식 상 전환법으로 theophylline이 각인된 poly(acryloni-trile-co-acrylic acid) 막을 제조하였다. theophylline은 고분자가 공중합되는 과정에 각인시키거나(in-situ implanting) 제자리 동시 각인) 공중합된 고분자를 DMSO 용액에 녹이면서 template를 섞어 각인시켰다(post implanting, 후 각인). 막의 template molecule에 대한 흡착 선택도는 응고시키는 물의 온도가 높을수록, 혼합물의 초기 농도가 높을수록 크게 나타났다. 후 각인법으로 제조된 막의 흡착선택도가 제자리 동시각인 제작법으로 제조된 막보다 흡착선택도가 우수하였다.

Keywords

References

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