Journal of Nutrition and Health

The Korean Nutrition Society (한국영양학회)
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Effects of Sodium Intakes on Blood Pressure and Blood Parameters in Korean Normal Adult Women

나트륨 섭취수준이 정상 성인 여성의 혈압과 혈액성상에 미치는 영향

  • 이영근 (수원여자대학 식품과학부) ;
  • 승정자 (숙명여자대학교 식품영양학과) ;
  • 최미경 (청운대학교 식품영양학과) ;
  • 이윤신 (수원여자대학 식품과학부)
  • Published : 2002.09.01
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Abstract

This study was performed to investigate the effect of sodium intake on blood pressure and blood parameters. 20 young adult women were fed the diets containing 290.5 mEq (high-Na diet) and 51.3 mEq (low-Na diet) Na for 6 days, respectively. BMI, DBP, and MBP were significantly lower in low-Na diet than those in high-Na diet. 20 subjects were divided into 3 groups according to the salt-sensitivity. In salt-sensitive group, decreases in SBP, DBP, and MBP by low-Na diet were shown. And there were not significant difference in blood pressure of salt-resistant group between high- and low-Na diet. In count-reactive group, MBP in low-Na diet was significantly higher than that in high-Na diet. Hemoglobin, creatinine, uric acid, and haptoglobin levels in serum were significantly higher in low-Na diet than those in high-Na diet. Among groups with different salt-sensitivity, increments of haptoglobin by low-Na diet were shown in salt-sensitive and counter-reactive groups. Actually, low sodium diet affects not only the blood pressure, but other biochemical parameters which in turn affect an individual overall health. Also salt-sensitivity should be considered as an important determinant. Therefore, for the patients who need restricted Na diet, it would be suggested that various biochemical changes and individual salt-sensitivity should be carefully considered along with dietary Na manipulation.

Keywords

References

  1. Arch Gen Med v.1 Causes de hypertension arterielle Ambard L;Beaujard E
  2. Am J Clin Nutr v.25 Salt and hypertension Dahl LK
  3. J Hum Hypertens v.15 no.4 Urinary calcium excretion, sodium intake and blood pressure in multiethnic population: results of the Wandsworth Heart and Stroke Study Blackwood AM;Sagnella GA;Cook DG;Cappuccio FP https://doi.org/10.1038/sj.jhh.1001171
  4. J Hum Hypertens v.16 no.3 Relation of urinary urea to blood pressure: interaction with urinary sodium Cirillo M;Lombardi C;Laurenzi M;De Santo NG https://doi.org/10.1038/sj.jhh.1001323
  5. J Clin Invest v.33 Artery wall electrolytes in renal and DCA hypertension Tobian L https://doi.org/10.1172/JCI103018
  6. Clin Sci v.12 Distribution of water, sodium and potassium in heart and skeletal muscle in experimental renal hypertension in rats Ledingham JM
  7. J Hypertens v.19 no.3 Effects of high sodium intake on cardiovascular aldosterone synthesis in stroke-prone spontaneously hypertensive rats Takeda Y;Yoneda T;Demura M;Furukawa K;Miyamori I;Mabuchi H https://doi.org/10.1097/00004872-200103001-00017
  8. Br J Cancer v.87 no.1 Dietary factors and stomach cancer mortality Ngoan LT;Mizoue T;Fujino Y;Tokui N;Yoshimura T;Yamakawa H https://doi.org/10.1038/sj.bjc.6600415
  9. Can J Gastroenterol v.14 no.S Nutrition and gastric cancer La Vecchia C;Franceschi S https://doi.org/10.1155/2000/324025
  10. Circulation v.52 Blood pressure, sodium intake, and sodium related hormones in the Yanomamo Indians, a no-salt culture Oliver WJ;Cohen EL;Neel JV https://doi.org/10.1161/01.CIR.52.1.146
  11. J Physiol v.530 no.1 Dietary restriction in pregnant rats causes gender-related hypertension and vascular dysfunction in offspring Ozaki T;Nishina H;Hanson MA;Poston L https://doi.org/10.1111/j.1469-7793.2001.0141m.x
  12. Am J Clin Nutr v.62 Dietary soduium restriciton in the prophylaxis of hypertensive disorders of pregnancy: effect on the intake of other nutrients Bert JA;Steegers, EAP;Jongsma HW;Rijpkema AL;Eskes TKAB;Thomas CMG;Baadenhuysen H;Hein PR
  13. Klin Wonchenschr v.69 no.S25 Short-term dietaty sodium restriction increases serum lipids and insulin in salt-sensitive and salt-resistant normotensive adults Ruppert M;Diehl J;Kolloch R;Overlack A;Kraft K;Gobel B;Hitte N;Stumpe KO https://doi.org/10.1007/BF01649060
  14. Klin Wochenschr v.69 no.S25 Potential deleterious impact of dietary salt restriction on cardiovascular risk factors Weder AB;Egan BM https://doi.org/10.1007/BF01649057
  15. Klin Wochenschr v.68 Dietary sodium restriction: adverse effect on plasma lipids Sharma AM;Arntz HR;Kribben A;Schatternfroh S;Distler A https://doi.org/10.1007/BF01667013
  16. Pol Merkuriusz Lek v.11 no.62 The role of sodium in prevention and treatment of essential hypertension Kobusiak-Prokopowicz M
  17. Am J Physiol Regul Integr Comp Physiol v.279 no.6 Mechanisms of salt-sensitive hypertension : role of inducible nitric oxide snythase Tan DY;Meng S;Cason GW;Manning RD
  18. Am J Hypertens v.13 no.11 Effects of isradipine or enalapril on blood pressure in salt sensitive hypertensives during low and high dietary salt intake Chrysant SG;Weder AB;McCarron DA;Canossa-Terris M;Cohen JD;Gunter PA;Hamilton BP;Lewin AJ;Mennella RF;Kirkegaard LW;Weir MR;Weinberger MH https://doi.org/10.1016/S0895-7061(00)01183-3
  19. J Hypertens v.19 no.10 Role of AT1 and AT2 receptor subtypes in salt-sensitive hypertension induced by sensory nerve degeneration Huang Y;Wang DH https://doi.org/10.1097/00004872-200110000-00019
  20. J Hum Hypertens v.15 no.7 Increased insulin resistance in salt sensitive essential hypertension Giner V;Coca A;de la Sierra A https://doi.org/10.1038/sj.jhh.1001216
  21. Recommended dietary allowances for Koreans(7th revision) The Korean Nutrition Society
  22. Food composition tables(5th Revision) National Rural Living Science Institute, RDA
  23. PhD thesis, Sookmyung Women's University Effect of sodium intake on plasma amino acid contents and macromineral metabolism in Korean adult women Hong WJ
  24. Essential Hypertension: An International Symposium Possible role of salt intake in the development of essential hypertension Dahl LK;Cottier P(ed.);Bock KD(ed.)
  25. BMJ v.302 Anaysis of data from trials of salt reduction Law MR;Frost CD;Wald NJ https://doi.org/10.1136/bmj.302.6780.819
  26. J Nephrol v.15 no.1 Salt intake and hypertension therapy Milan A;Mulatero P;Rabbia F;Veglio F
  27. J Hum Hypertens v.16 no.7 Blood pressure and urinary excretion of electrolytes in Spanish schoolchildren Maldonado-Martin A;Garcia-Matarin L;Gil-Extremera B;Aviva-Oyonarte C;Garcia-Granados ME;Gil-Garcia F;Latorre-Hernandez J;Miro-Gutierrez J;Soria-Bonilla A;Vergara-Martin J;Javier-Martinez MR https://doi.org/10.1038/sj.jhh.1001424
  28. Ann Int Med v.98 no.P2 Role of a natriuretic factor in essential hypertension. An hypothesis Blaustein MP;Hamlyn JM https://doi.org/10.7326/0003-4819-98-5-785
  29. Clin Exp Pharmacol Physiol v.28 no.12 Interaction between sodium and angiotensin Morgan T https://doi.org/10.1046/j.1440-1681.2001.03577.x
  30. Circulation v.86 no.5 A prospective study of nutritional factors and hypertension among US men Alberto A;Rimm EB;Giovannucci EL;Colditz GA;Willett WC;Stampfer MJ https://doi.org/10.1161/01.CIR.86.5.1475
  31. QJM v.93 no.8 Diastolic blood pressure is related to urinary sodium excretion in hypertensive Chinese patients Cheung BM;Ho SP;Cheung AH;Lau CP https://doi.org/10.1093/qjmed/93.8.557
  32. Clin Chem Lab Med v.40 no.3 Haptoglobin polymorphism and body iron stores Delanghe JR;Langlois MR https://doi.org/10.1515/CCLM.2002.035
  33. Hypertension v.17 no.S1 Salt sensitibity and resistance of blood pressure. Age and race as factors in physiological responses Luft FC;Miller JZ;Grim CE;Fineberg NS;Chirstian JC;Daugherty SA;Weinberger MH
  34. Hypertension v.10 Association of haptoglobin with sodium sensitivity and resistance of blood pressure Weinberger MH;Miller JZ;Finberg NS https://doi.org/10.1161/01.HYP.10.4.443
  35. Rev Port Cardiol v.21 no.1 Blood pressure and genetic and biological markers in pediatric population Guerra A;Rego C;Silva D;Rodrigues P;Silva Z;Breitenfeld L;Pinto AT;Bicho M