Pediatric Gastroenterology, Hepatology & Nutrition

The Korean Society of Pediatric Gastroenterology, Hepatology and Nutrition (대한소아소화기영양학회)
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A Case of Eosinophilic Colitis in a 11-year-old Boy

호산구성 대장염 1례

  • Nah, Joo-Hee (Department of Pediatrics, The Catholic University of Korea College of Medicine) ;
  • Park, Young-Shil (Department of Pediatrics, The Catholic University of Korea College of Medicine) ;
  • Kim, Sun-Mi (Department of Pediatrics, The Catholic University of Korea College of Medicine) ;
  • Lee, Jung-Hyun (Department of Pediatrics, The Catholic University of Korea College of Medicine) ;
  • Jeong, Dae-Chul (Department of Pediatrics, The Catholic University of Korea College of Medicine) ;
  • Kim, Jin-Tack (Department of Pediatrics, The Catholic University of Korea College of Medicine) ;
  • Chung, Seung-Yun (Department of Pediatrics, The Catholic University of Korea College of Medicine) ;
  • Lee, An-Hi (Department of Pathology, The Catholic University of Korea College of Medicine) ;
  • Kang, Jin-Han (Department of Pediatrics, The Catholic University of Korea College of Medicine) ;
  • Lee, Joon-Sung (Department of Pediatrics, The Catholic University of Korea College of Medicine)
  • 나주희 (가톨릭대학교 의과대학 소아과학교실) ;
  • 박영실 (가톨릭대학교 의과대학 소아과학교실) ;
  • 김선미 (가톨릭대학교 의과대학 소아과학교실) ;
  • 이정현 (가톨릭대학교 의과대학 소아과학교실) ;
  • 정대철 (가톨릭대학교 의과대학 소아과학교실) ;
  • 김진택 (가톨릭대학교 의과대학 소아과학교실) ;
  • 정승연 (가톨릭대학교 의과대학 소아과학교실) ;
  • 이안희 (가톨릭대학교 의과대학 병리학교실) ;
  • 강진한 (가톨릭대학교 의과대학 소아과학교실) ;
  • 이준성 (가톨릭대학교 의과대학 소아과학교실)
  • Received : 2002.03.07
  • Accepted : 2002.03.20
  • Published : 2002.03.30
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Abstract

Eosinophilic gastroenteritis, which shows characteristic eosinophilic inflammation, involves any part of the intestine from esophagus to colon. The immunopathogenesis is expected to be associated with IgE-mediated or non-IgE-mediated reaction, but the precise mechanism is not revealed yet. The clinical manifestation is variably dependent on the extent of eosinophilic infiltration. Usually the symptoms, such as abdominal pain, diarrhea, vomiting, wax and wane for a few months result in failure to thrive, which implicates the importance of early detection. Although the diagnosis is made through clinical and histopathologic evidences, we should suspect the illness in a case of anemia, hypoalbuminemia, and peripheral eosinophilia. Recently, we experienced a case of non-IgE-mediated eosinophilic colitis in a 11-year-old male who complained of diarrhea, right lower abdominal pain, body weight loss, was diagnosed with peculiar histopathologic finding of sigmoid colon specimens obtained by sigmoidoscopy.

저자들은 설사와 우복부통증 및 체중감소의 증상을 보인 11세 남아에서 말초혈액의 호산구수 증가와 IgE가 정상범위이며 대장내시경하에 채취한 S자결장 생검조직에서 특징적인 호산구침윤 소견이 관찰되어 비 IgE 매개성 호산구성 대장염으로 진단된 1례를 경험하였으며 부신피질 호르몬 투여로 증상 호전을 보여 문헌고찰과 함께 보고하는 바이다.

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