Natural Product Sciences

The Korean Society of Pharmacognosy (한국생약학회)
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Cuneifolin, a New Xanthone from Garcinia cuneifolia (Guttiferae)

  • Ee, G.C.L. (Department of Chemistry, Faculty of Science and Environmental Studies University Putra Malaysia) ;
  • Phong, K.H. (Department of Chemistry, Faculty of Science and Environmental Studies University Putra Malaysia) ;
  • Mong, X.H. (Department of Chemistry, Faculty of Science and Environmental Studies University Putra Malaysia) ;
  • Shaari, K. (Department of Chemistry, Faculty of Science and Environmental Studies University Putra Malaysia) ;
  • Sukari, M.A. (Department of Chemistry, Faculty of Science and Environmental Studies University Putra Malaysia)
  • Published : 2003.09.01
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Abstract

Studies on the stem bark extracts of Garcinia cuneifolia have furnished a new xanthone cuneifolin (1) and the triterpene stigmasterol (2). Structures for these compounds were elucidated based on NMR, 2D NMR, MS and GCMS data. Larvicidal activity screening of the crude bark extract using the larvae of Aedes aegypti indicated the larvae to be susceptible to these extracts. $LC_{50}$ values of the bioassays show the extracts to be moderately toxic to the larvae of Aedes aegypti.

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References

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