Natural Product Sciences

The Korean Society of Pharmacognosy (한국생약학회)
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Effect of Hexane Extract of Acori graminei Rhizoma on the Growth of Chloramphenicol Resistant Bacteria

  • Published : 2003.09.01
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Abstract

The combination of hexane extract (E4) of rhizome of Acorus gramineus with chloramphenicol (Cm) was applied to Gram negative Cm resistant microbials to find the possibility of clinical use and to clarify the relationship of the activity of chloramphenicol acetyltransferase (CAT). The combination of $1,000\;{\mu}g/ml$ of E4 and $8\;{\mu}g/ml$ of Cm entirely ceased the growth of S. aureus SA2, a gram positive resistant strain to 10 antibiotics. But in Gram negative strains which possess CAT activity, some showed considerably strong resistances to Cm and some did weakly.

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References

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