Herbal Formula Science (대한한의학방제학회지)

The Korean Medicine Society for the Herbal Formula Study (대한한의학방제학회)
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Effects of Jakyakgamchotang extract on the Analgesic effect in Mice

작약감초탕(芍藥甘草湯) 및 구성약물(構成藥物)이 진통(鎭痛)에 미치는 영향(影響)

  • Lee Ki-Ok (Departments of prescription, in Oriental Medicine Wonkwang University) ;
  • Kuk Yun-Beum (Department of Oriental Medicine Prescription Sangji University) ;
  • Yun Young-Gab (Departments of prescription, in Oriental Medicine Wonkwang University)
  • 이기옥 (원광대학교 한의과대학 방제학교실) ;
  • 국윤범 (상지대학교 한의과대학 본초방제학교실) ;
  • 윤용갑 (원광대학교 한의과대학 방제학교실)
  • Published : 2003.06.20
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Abstract

This study was designed to elucidate the analgesic effects of Jakyakgamchotang and Radix paeinia, Radix Glycyrrhiziae which are the component of Jakyakgamchotang in mice. The analgesic effects were measured by the Whittle's method and hot plate method. The results were as follows ; After the administration of Jakyakgamchotang extrace, the frequency of writhing syndrome was significantly inhibited. After the administration of Radix paeinia extract, the frequency of writhing syndrome was significantly inhibited. After the administration of Radix Glycyrrhiziae extract, the frequency of writhing syndrome was significantly inhibited. After the administration of Jakyakgamchotang extrace, paw licking time and escape time were significantly prolonged. After the administration of Radix paeinia extract, paw licking time was significantly prolonged. After the administration of Radix Glycyrrhiziae extract, paw licking time was significantly prolonged. It is concluded that the analgesic effects of Jakyakgamchotang were found to be more effective than Radix paeinia and Radix Glycyrrhiziae.

Keywords

References

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