Korean Journal of Acupuncture

Society for Meridian and Acupoint (경락경혈학회)
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Effect of Sophorae Flos Aqua-acupuncture Solution on the Quinone Reductase and Glutathione S-transferase Activities of Hepa 1c1c7 Cells

괴화약침액이 간세포의 Quinone redutase 와 Glutathione S-transferase 활성에 미치는 영향

  • Lee Ki-Taek (Dept. of Meridian & Acupoint, College of Oriental Medicine, Dongguk University) ;
  • Lim Jong-Kook (Dept. of Meridian & Acupoint, College of Oriental Medicine, Dongguk University)
  • 이기택 (동국대학교 한의과대학 경혈학교실) ;
  • 임종국 (동국대학교 한의과대학 경혈학교실)
  • Published : 2003.03.27
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Abstract

Sophorae Flos aqua-acupuncture solution(SFAS) was prepared and tested for the induction of quinone reductase and glutathione S-transferase activities and glutathione. SFAS significantly induced QR activity at the concentrations of $0.5{\times},\;1{\times}\;and\;3{\times}$ in cell culture. However, GST activity in murine Hepa 1c1c7 cells was slightly increased with SFAS. SFAS increased GSH levels.

괴화약침액이 간세포의 quinone reductase, glutathione S-transferase 와 환원형 glutathione의 활성에 미치는 영향을 살펴 본 결과 괴화약침액은 암예방 효소인 Phase II enzyme을 유의성 있게 증가 시켰다. 따라서 괴화약침액은 암예방에 효과가 있는 것으로 사료된다.

Keywords

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