Journal of Society of Preventive Korean Medicine (대한예방한의학회지)

Society of Preventive Korean Medicine (대한예방한의학회)
권호 표지

Cytotoxic Effects of Methanol Extracts from Saururus Chinensis Bail and Herba Houttuyniae on Cancer Cell Lines

삼백초(三白草)와 어성초(魚腥草)의 암세포(癌細胞)에 대한 독성억제(毒性抑制) 효과(效果)

  • Han Sang-Youp (Dept. of Third Medicine, Professional Graduate School, Wonkwang University) ;
  • Lee Jeong-Ho (Dept. of Third Medicine, Professional Graduate School, Wonkwang University) ;
  • Baek Seung-Hwa (Department of Herbal Resources, Professional Graduate School of Oriental Medicine, Wonkwang University) ;
  • Lee Taek-Jun (Preventive Medicine, College of Oriental Medicine Wonkwang University) ;
  • Song Yong-Sun (Dept. of Third Medicine, Professional Graduate School, Wonkwang University) ;
  • Lee Ki-Nam (Dept. of Third Medicine, Professional Graduate School, Wonkwang Universityc)
  • 한상엽 (원광대학교 한의학전문대학원 제3의학과) ;
  • 이정호 (원광대학교 한의학전문대학원 제3의학과) ;
  • 백승화 (원광대학교 한의학전문대학 한약자원개발학과) ;
  • 이택준 (원광대학교 대학원 한의학과) ;
  • 송용선 (원광대학교 한의학전문대학원 제3의학과) ;
  • 이기남 (원광대학교 한의학전문대학원 제3의학과)
  • Published : 2003.12.29
Download PDF
⟨ Previous Next ⟩

Abstract

This study was performed to determine the cytotoxic effect of methanol extract from medicinal plants. 1. The cell viability was determined by MTT method. Their cytotoxic activities against three cancer cell lines such as A549, MDA-MB-231 and SNU-C4 cell line were tested. 2. Among them, The methanol extract of Saururus Ohinensis Bail showed the strongest cytotoxic effect against SNU-C4 cells. These results suggest that the methanol extract of Saururus Ohinensis Bail possessed a potential antitumorous agent. 3. The free radical scavenging activity using DPPH method was the strongest of Saururus Chinensis Bail extract.

Keywords

References

  1. Kor, J. Postharvest Sci. Technol v.8 no.2 Effect of water extract from Saururus Chinensis(Lour.) Bail water extracts on the cancer cells and antioxidative activity in cytotoxicity Lee, I.S.
  2. Korean Home Economics Association v.38 no.1 The dyeability and antimicrobial activity of Saururus Chinensis(I) Kim, B.H.;Song, W.S.
  3. Annals of Botany v.84 Evidence for stigmatic self-incompatibility, pollination induced ovule enlargement and transmitting tissue exudates in the paleoherd, Saururus cernuus L.(Saururacese) Pontieri, V.;Lynn Sage, T.
  4. Korean J. Medicinal Crop Sci v.6 no.4 Effects of tuber pasition and number of nodes on growth of Saururus Chinensis Baill Park, J.H.;Park, B.G.;Kim, M.J.;Park, S.G.;Kim, J.H.
  5. Korean J. Medicinal Crop Sci v.8 no.4 Component comparison in different growth stages and organs of Saururus chinensis BAILL Lee, S.T.;Park, J.M.;Lee, H.K.;Kim, M.B.;Cho, J.S.;Heo, J.S.
  6. 原色臨床本草學 辛民敎
  7. 大韓植物圖鑑 李昌福
  8. 原色天然物事典 v.下 金在佑
  9. 中藥大事典 小學館
  10. 常用中草藥手冊 商務印書館
  11. 圖解本草綱目 李時珍
  12. 天然物醫藥品學 系川秀池
  13. 中藥大辭典 江蘇新醫學院
  14. 中藥藥理與應用 王裕生
  15. 中藥學 周鳳梧
  16. Yakhak Hoeji v.41 no.6 Studies on the cytotoxic constituent of Saururus chinensis(LOUR) BAILL Park, S.K.;Oh, G.J.;Bae, C.I.;Kim, H.J.;Han, W.S.;Chung, S.G.;Cho, E.W.
  17. Yakhak Hoeji v.46 no.6 The inhibitory effect on the function of E6 and E7 Oncogenes of HIV type 16 Chung, Y.G.;Lee, H.S.;Lee, K.A.;Joung, O.;Oh, W.K.;Kim, K.D.;Lim, J.S.;Moon, J.Y.;Cho, Y.K.;Park, S.N.;Yoon, D.Y.
  18. Kor. J. Oriental Preventive Medical Society v.4 no.1 Studies on the cytotoxicity and antimicrobial effects of the extract of Houttuynia Cordata(IV) Lee, J.H.;Park, N.K.;Yang, E.Y.;Lee, H.O.;Han, D.M.;Baek, S.H.
  19. Kor. J. Pharmacogn v.32 no.1 The inhibitory effects of the methanol extracts of Houttuynia cordata THUNB against cadmium induced cytotoxicity (V) Lee, J.H.;Jeong, S.I.;You, I.S.;Kim, S.K.;Lee, K.N.;Han, D.S.;Baek, S.H.
  20. J. Korean Chemical Society v.47 no.2 The inhibitory effects of quercitrin fron Houttuynia Cordata against cadmium induced cytotoxicity(VII) Lee, J.H.;Lee, K.N.;Lee, C.W.;Chun, H.J.;You, I.S.;Lim, J.A.;Baek, S.H.
  21. Chem. Pharm. Bull v.36 no.5 Platelet aggregation inhibitors from Jyu-yaku (HouttuyniaeHerb) Nishiya, H.;Ishiwata, K.;Komatsu, K.;Nakata, O.;Kitamura, K.;Fujh, S.
  22. Kor, J, Pharmacogn. v.27 no.1 Comparison of antioxidant and composition in Glycine max Merr and Glycine soja Siebold et Zucc Cha, B.C.;Park, H.J.;Lee, E.;Cho, M.Y.;Rhim, T.J.
  23. J. Plant Biol. v.38 no.1 Genetic diversity in korean populations of Glycine soja(Fabaceae) Chung, S.D.;Hong, W.H.;Myong, G.C.
  24. Kor. J. Pharmacogn. v.33 no.4 Cytotoxicity of methanol extracts of edible herbs against L1210 cells with the changes of antioxidant enzymes activities Kim, S.J.;Cho, Y.S.;Park, S.W.
  25. J. Korean Soc. Food Sci. Nutr. v.32 no.2 Antioxidative, Antimutagenic and cytotoxic effects of Rhodiola sachalinensis extract Cui, C.B.;Lee, D.S.;Ham, S.S.
  26. Korean Nutrition Society v.35 no.1 Green tea(-)EGCG induces the apoptotic death og lung cancer cells via activation of c-Jun N-terminal 1 and activating protein-1 Park, J.S.;Shin, M.K.;Shn, H.S.;Park, R.K.;Kim, M.S.;Eong, W.H.
  27. Korean J. Oriental Physiology & Pathology v.16 no.3 The water extract of caesalpinia sappan induces apoptosis on human lung cancar call line, A549 cells Mun, Y.J.;Nam, Y.J.;Lee, K.G.;Chol, D.H.;Lee, S.W.;Ahn, S.H.;Chol, M.K.;Woo, W.H.
  28. Korean J. Medicinal Crop Sci v.11 no.1 Growth enhancement and cytotoxicity of Korean mistletoe fractions on human cell lines Lee, S.J.;Lee, M.K.;Choi, G.P.;Yu, C.Y.;Roh, S.K.;Kim, J.D.;Lee, H.Y.;Lee, J.H.
  29. Korean J. Medicinal Crop Sci v.10 no.3 Effect of antioxidant, antimutagenicity and anticancer or root extract from Ixeris dentata Nakai Kim, M.J.;Kim, J.S.;Jeong, D.M.;Ham, S.S.;Yu, C.Y.
  30. Korean J. Medicinal Crop Sci v.11 no.1 Antimutagenicity and anticancer activities of extraacts from Cirsium japonicum var. ussuriense KITAMURA Lee, H.K.;Kim, J.S.;Kim, N.Y.;Kim, M.J.;Park, S.U.;Yu, C.Y.
  31. Kor. J. Pharmacogn v.32 no.4 Induction of apoptosis in Jurkat T Lymphocytes by extract of Ailanthus altissima Hwang, S.K.;Lee, H.C.;Kim, C.K.;Chun, H.J.;Jeung, S.I.;Jeon, B.H.
  32. Kor. J. Pharmacogn v.27 no.3 Isolation of anticancer agents from the leaves of Platycarya strobilacea S. et Z. Kim, Y.I.;Lee, S.H.;Cho, T.S.
  33. Kor. J. Orient. Physiol. & Pathol. v.16 no.2 screening of Cytotoxicity and Antimicrobial effects of extracts from Atractylades macrocephala Koidz Choi, E.Y.;Oh, H.J.;Park, N.K.;Chun, H.J.;Ahn, J.W.;Jeon, B.H.;Han, D.S.;Lee, H.D.;Baek, S.H.
  34. J, Ginseng, Res. v.23 no.2 Antioxidant activity of the water soluble browning reaction proucts isolated from korean Red Ginseng, 1. DPPH radical and hydrogen peroxide scavenging Lee, J.W.;Do, J.H.;Shin, K.H.
  35. Korean, J, Crop, Sci v.45 no.4 Varietal variation in antioxidative activity of rice grain by DPPH and TBA methods Chung, I.M.;Kim, K.H.;Ahn, J.K.;Lee, J.D.
  36. Mokchae konghak v.30 no.4 Studies on biological activity of wood extractive (IX) - Antioxidative compounds from heartwood of Robinia pseudo acacia Choi, D.H.;Lee, H.J.;Lee, S.S.;Kim, J.G.;Kang, H.Y.
  37. J, Korean Soc, Agric, Chem, Biotechnl v.46 no.1 Screening of antioxidative activity of legume species Nam, S.H.;Kang, M.Y.
  38. Korean J. Medicinal Crop Sci v.11 no.1 The activity of antioxidants and suppression of cancer cell proliferation in extracts of Orostachys japonicus. A, Berger Kim, C.H.;Park, J.H.;Lim, J.K.;Lee, K.J.;Chung, G.Y.;Jeong, H.J.
  39. Kor, J, Pharmacogn v.29 no.3 Antioxidative compounds isolated from the stem bark of eucalyptus globulus Lee, I.K.;Yun, B.S.;Kim, J.P.;Chung, S.H.;Shin, G.S.;Yoo, I.D.
  40. J. Immunol. Methods v.65 Rapid colorimetric assays for cellular growth and survival : application to proliferation and cytotoxicity assays Mosmann, T.
  41. Eur. J. Cancer v.27 Comparison of the sulforhodamine B protein and tetrazolium(MTT) assays for in vitro chemosensitivity testing Keepers, Y.P.;Pozao, P.E.;Peters, G.T.;Otte, J.A.;Winograd, B.;Pinedo, H.M.
  42. Biol. Pharm. Bull v.19 Antioxidative effects of phenylethanoids from Cistanche deserticola Xiong, Q.;Kadota, S.;Tadata, T.;Namba, T.
  43. Kor. J. Pharmacogn v.33 no.4 Antioxidant effects of the extracts of Acanthopanax senticosus Jin, L.H.;Han, S.S.;Choi, Y.S.