Biotechnology and Bioprocess Engineering:BBE

The Korean Society for Biotechnology and Bioengineering (한국생물공학회)
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Regioselective Enzymatic Acylation of Multi-hydroxyl Compounds in Organic Synthesis

  • Park, Hyun-Gyu (Department of Chemical and Biomolecular Engineering, Korea Advanced Institute of Science and Technology) ;
  • Do, Jin-Hwan (Department of Chemical and Biomolecular Engineering, Korea Advanced Institute of Science and Technology) ;
  • Chang, Ho-Nam (Department of Chemical and Biomolecular Engineerring, Korea Advanced Institute of Science and Technology)
  • Published : 2003.01.01
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Abstract

With current developments in enzyme-catalyzed reactions and techniques available for rational redesign of natural biocatalysts, the enzymatic biosynthesis can become one of the most valuable Synthetic methods. Enzymatic regioselective catalysis in organic media has played a key role in pursuing asymmetric synthesis for active chiral compounds. Here, we shortly do-scribe some historical issues of the rapidly growing area, enzymatic catalysis in synthetic organic chemistry and then review researches that have been carried out in the regioselective enzymatic catalysis for the past two decades. An application of this technology to the modification of some potential target drug co m pound will be adios presented.

Keywords

References

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