Archives of Pharmacal Research

  • 제26권11호
  • /
  • Pages.925-928
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  • 2003
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  • 0253-6269(pISSN)
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  • 1976-3786(eISSN)
대한약학회 (The Pharmaceutical Society of Korea)
권호 표지

Cytotoxic Effects of Sesquiterpene Lactones from the Flowers of Hemisteptia Iyrata B.

  • Ha, Tae-Joung (Institute of Agriculture and Life Science, Gyeongsang National University) ;
  • Jang, Dae-Sik (Graduate School of Molecular Life Sciences, Ewha Womans University) ;
  • Lee, Jong-Rok (Department of Agricultural Chemistry, Division of Applied Life Science, Gyeongsang National University) ;
  • Lee, Kyung-Dong (Institute of Agriculture and Life Science, Gyeongsang National University) ;
  • Lee, Jun (Department of Agricultural Chemistry, Division of Applied Life Science, Gyeongsang National University) ;
  • Hwang, Seon-Woo (Department of Agricultural Chemistry, Division of Applied Life Science, Gyeongsang National University) ;
  • Jung, Hwa-Jin (Department of Agricultural Chemistry, Division of Applied Life Science, Gyeongsang National University) ;
  • Nam, Sang-Hae (Department of Food Processing, Chinju National University) ;
  • Park, Ki-Hun (Department of Agricultural Chemistry, Division of Applied Life Science, Gyeongsang National University) ;
  • Yang, Min-Suk (Institute of Agriculture and Life Science, Gyeongsang National University)
  • 발행 : 2003.11.01
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초록

Four guaia-12,6-olide type sesquiterpene lactones, aguerin B (1), 8$\alpha$-acetoxyzaluzanin C (2), cynaropicrin (3), and deacylcynaropicrin (4), were isolated from the flowers of Hemisteptia Iyrata Bunge. It is the first report on the isolation of compounds 1-4 from Hemisteptia species. All the isolates (1-4) were examined for their cytotoxic activity against SK-OV-3, LOX-IMVI, A549, MCF-7, PC-3, and HCT-15 human cancer cell lines.

키워드

참고문헌

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