Mycobiology

The Korean Society of Mycology (한국균학회)
권호 표지
DOI QR코드

DOI QR Code

In vitro Evaluation of Antidermatophytic Activity of Egyptian Bee Propolis in Combination with Plant Essential Oils in Sheep Hoof Plate: An Experimental Model

  • Mahmoud, Yehia A.G. (Tanta University, Faculty of Science, Botany Department, Mycology research lab.)
  • Published : 2003.06.30
Download PDF
⟨ Previous Next ⟩

Abstract

Bee propolis ethanolic extract with some plant essential oils was investigated for its antidermatophytic properties. The tested plant essential oils included jasmine, clove, lemon, Arabian jasmine, mint, rosa, olive and basil. The antidermatophytic activity has been compared to Naftifine-HCl and Clotrimazole used for dermatophyte treatment. Experimental model has been tested using sheep hoof plate for the in vitro tests to stimulate human nails. Mint, clove and basil with 4 mg/ml of bee propolis have a comparable efficacy to those of Naftifine-HCl and Clotrimazole. There is a great necessity for new effective low price and safe antidermatophyte agents to avoid recurrent infection. Propolis synergistic could be of great importance with essential oils of plants in dermatophyte therapy.

Keywords

References

  1. Ahmed, S. K. and Agnihotri, J. P. 1977. Antifungal activity of some plant extracts. Indian. J. Mycology and Plant Pathol. 7:180-181
  2. Al-Doory, Y. 1980. Media in Lea and Febiger (eds.). Laboratory Medical Mycology, Henry Kimpton London, pp, 357-375
  3. Benfields, P. and Clissold, S. P. 1988. Sulconazole: a review of its antimicrobial activity and therapeutic use in superficial dermat-omycosis. Drugs Auckland. 35: 143-153 https://doi.org/10.2165/00003495-198835020-00004
  4. Callejo, A., Armentia, A., Lombardero, M., Martinez, C, Rebollo, S., Sedano, E., de la Fuente, R. and Fernandez, A. 2001. Case report, hypersensitivity to propolis. Alergol lmmunol Clin. 16:113-117
  5. Ceshin-Roques, C. G., Hanel, H., Pruja-Bougaret, S. M., Luc, J., Vandermander, J. and Michel, G. 1991. Ciclopirox nail lacquer 80%: in vivo penetration into and through nails and in vitro effect on pig skin. Skin Pharmacol. 4: 89-94 https://doi.org/10.1159/000210929
  6. Cohen, P. R. and Richard, K. S. 1994. Topical and surgical treatment of onchomycosis. J.Amer.Acad.Dermatol. 3: 68-74
  7. Cowan, M. M. 1999. Plant products as antimicrobial agents. Clinical Microbial. Rev.12: 564-582
  8. Cox, S. D., Mann, C. M., Markham, J. L., Bell, H. C., Gustafson, J. E., Warmington, J. R. and Wyllie, S. G. 2000. The mode of antimicrobial action of the essential oil of Melaleuca alternifolia (tea tree oil). J. Appl. Microbiol. 88: 170-175 https://doi.org/10.1046/j.1365-2672.2000.00943.x
  9. Deshnukh, S. K., Jain, P. C. and Agrawal, S. C. 1986. A note on mycotoxicity of some essential oils. Fitoterapia 57: 295-297
  10. EI-Naghy, M. A., Maghazy, S. N., Fadl-Allah, E. M. and EI-Gendy, Z. K. 1992. static action of natural oils and fatty acids on dermatophytic and saprophytic fungi. Zentralbl. Mikrobiol. 147: 214-220
  11. Hemidy, P. Y., Makki, S., Muret, P., Chaumont, J. P. and Millet, J. 1994. The use of sheep hoof plates for substituting human nails in transungual absorption studies. J. Appl. Cosmetol. 12: 73-84
  12. Inouye, S., Tsuruoka, A., Watanabe, S., Takeo, K., Akao, O., Nishiyama, Y. and Yamaguchi, M. 2000. Inhibitory effects of essential oils on apical growth of Aspergillus fumigatus by vapour contact. Mycoses 43: 17-23 https://doi.org/10.1046/j.1439-0507.2000.00538.x
  13. Mahmoud, A. L. E. 1991. Some physiological and biochemical studies on fungi isolated from skin of mammals. Ph.D. Thesis, Bot. dept., Fac. Sci. Assiut Univ., Egypt
  14. Malecky, J. C. and McClausland, J. P. 1982. In vitro penetration and absorption of chemicals into the ovine hoof. Res. veterin. Sci. 33: 192-197
  15. Moharram, A. M. 1999. Comparison of the effect of allylamine and azole derivatives on fungi isolated from human nails. Bull. Fac. Sci. Assiut univ. 28(2-D): 21-33
  16. Sainsbury, M. and Sofowora, E. A. 1971. Essential oil from the leaves and inflorescence of Ocimum gratissimum. Phytochemistry 10: 3309-3310 https://doi.org/10.1016/S0031-9422(00)97406-5
  17. Vincent, J. M. 1927. Distortion of fungal hypha in the presence of certain inhibitors. Nature 159: 850
  18. Williams, H. C. 1993. The epidemiology of onychomycosis in Britain. Br. J. Dermat. 129: 101-109 https://doi.org/10.1111/j.1365-2133.1993.tb03510.x

Cited by

  1. Use of Propolis for Topical Treatment of Dermatophytosis in Dog vol.04, pp.10, 2014, https://doi.org/10.4236/ojvm.2014.410028