A fMRI study on the cerebral activity induced by Electro-acupuncture on K7(Fuliu)

복류(復溜)(K7) 전침자극(電鍼刺戟)이 functional MRI상 뇌기능(腦機能) 변화(變化)에 미치는 영향(影響)

  • Kang, Jae-hui (Department of Acupuncture & Moxibustion College of Oriental Medicine, Dae-Jeon University) ;
  • Lee, Hyun (Department of Acupuncture & Moxibustion College of Oriental Medicine, Dae-Jeon University) ;
  • Lee, Byung-ryul (Department of Acupuncture & Moxibustion College of Oriental Medicine, Dae-Jeon University) ;
  • Hong, Kwon-eui (Department of Acupuncture & Moxibustion College of Oriental Medicine, Dae-Jeon University) ;
  • Yim, Yun-kyoung (Department of Acupuncture & Moxibustion College of Oriental Medicine, Dae-Jeon University) ;
  • Kim, Yun-jin (Department of Diagnosit Radiology Hae-Hwa Hospital, Dae-Jeon University)
  • 강재희 (대전대학교 한의과대학 침구경혈학교실) ;
  • 이현 (대전대학교 한의과대학 침구경혈학교실) ;
  • 이병렬 (대전대학교 한의과대학 침구경혈학교실) ;
  • 홍권의 (대전대학교 한의과대학 침구경혈학교실) ;
  • 임윤경 (대전대학교 한의과대학 침구경혈학교실) ;
  • 김연진 (대전대학교 부속혜화병원 진단방사선과)
  • Received : 2003.07.02
  • Accepted : 2003.07.12
  • Published : 2003.08.20

Abstract

Objectve : Recent stuides suggested that there is a strong correlation between acupuncture stimulation and its cortical activation. Another study showed that either positive or negative BOLD effects could be observed depending on anatomical structure in acupuncture. Methods : 1) Subjects and paradigms: Two separate stimulation paradigms were performed in this study. To see the effects of electro-acupuncture stimulation on K7(Fuliu), the experiment was carried out on six healthy volunteers, using the gradient echo sequence with the 3.0T whole-body MRI system(ISOL). After the needle insertion on right K7(Fuliu), 2 Hz of electric stimulation was given for 30 seconds, repeated five times, with 30 seconds' intervals. During the intervals while there was no electro-stimulation, the subjects performed motor task as a reference. The image analysis including motion correction, talairach transformation, and smoothing was done using SPM99. Results: The electro-acupuncture stimulation on K7(Fuliu) activated Brodmann's Areas of 9, 19, 23, 24, 31, 32, 39 which may be the central pathways of the electro-acupuncture stimulation on K7(Fuliu) and those brain areas may be related with the function of the electro-acupuncture stimulation on K7(Fuliu).

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