Annals of Clinical Neurophysiology
- Volume 5 Issue 1
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- Pages.21-26
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- 2003
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- 2508-691X(pISSN)
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- 2508-6960(eISSN)
Lower Motor Neuron Hyperexcitability in Amyotrophic Lateral sclerosis: Analysis Using Motor Evoked Potentials
근위축성 측삭 경화증의 하 운동 신경원 과흥분성: 운동유발전위를 이용한 분석
- Bae, Jong-Seok (Department of Neurology Samsung Medical Center School of Medicine Sungkyunkwan University) ;
- Hong, Suk-Chan (Department of Neurology Samsung Medical Center School of Medicine Sungkyunkwan University) ;
- Kim, Min-ky (Department of Neurology Kang-Nam general hospital public corporation) ;
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Kim, Byoung-Joon
(Department of Neurology Samsung Medical Center School of Medicine Sungkyunkwan University)
- 배종석 (성균관대학교 의과대학 삼성서울병원 신경과학교실) ;
- 홍석찬 (성균관대학교 의과대학 삼성서울병원 신경과학교실) ;
- 김민기 (지방공사 강남병원 신경과학교실) ;
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김병준
(성균관대학교 의과대학 삼성서울병원 신경과학교실)
- Published : 2003.05.10
Abstract
Background & Objectives: Hyperexcitablity of motor system is a well-established characteristic pathophysiologic finding of amyotrophic lateral sclerosis (ALS). Whereas little is known about the source of excitability according to the progression of the disease. We evaluated the excitability and its source in advanced ALS patients using transcranial magnetic stimulation (TMS). Meterial & Methods: Motor evoked potentials (MEP) by TMS were recorded for abductor pollicis brevis muscles in 20 patients, 11 men and 9 women, with ALS. Mean age was