Korean Journal of Veterinary Research (대한수의학회지)

The Korean Society of Veterinary Science (대한수의학회)
권호 표지

The postnatal development of the rat Leydig cell

흰쥐에서 출생후 고환 간질세포의 발생

  • Tae, Hyun-Jin (College of Veterinary Medicine, Chonbuk National University) ;
  • Li, Li-Guang (College of Veterinary Medicine, Chonbuk National University) ;
  • Park, Byung-Yong (College of Veterinary Medicine, Chonbuk National University) ;
  • Park, Young-Jae (College of Veterinary Medicine, Chonbuk National University) ;
  • Choi, Eun-Young (College of Veterinary Medicine, Chonbuk National University) ;
  • Lee, Young-Hoon (School of Dentistry, Chonbuk National University) ;
  • Ahn, Dong-Choon (Department of Veterinary Medicine, Kangwon National University) ;
  • Kang, Hyung-Sub (Bio-Safety Research Institute, College of Veterinary Medicine, Chonbuk National University) ;
  • Park, Sang-Youel (Bio-Safety Research Institute, College of Veterinary Medicine, Chonbuk National University) ;
  • Park, Soo-Hyun (Bio-Safety Research Institute, College of Veterinary Medicine, Chonbuk National University) ;
  • Lee, John-Hwa (Bio-Safety Research Institute, College of Veterinary Medicine, Chonbuk National University) ;
  • Yang, Hong-Hyun (Bio-Safety Research Institute, College of Veterinary Medicine, Chonbuk National University) ;
  • Kim, In-Shik (Bio-Safety Research Institute, College of Veterinary Medicine, Chonbuk National University)
  • 태현진 (전북대학교 수의과대학) ;
  • 이여광 (전북대학교 수의과대학) ;
  • 박병용 (전북대학교 수의과대학) ;
  • 박영재 (전북대학교 수의과대학) ;
  • 최은영 (전북대학교 수의과대학) ;
  • 이영훈 (전북대학교 치과대학 해부학교실) ;
  • 안동춘 (강원대학교 수의학과) ;
  • 강형섭 (전북대학교 수의과대학 생체안전성연구소) ;
  • 박상열 (전북대학교 수의과대학 생체안전성연구소) ;
  • 박수현 (전북대학교 수의과대학 생체안전성연구소) ;
  • 이존화 (전북대학교 수의과대학 생체안전성연구소) ;
  • 양홍현 (전북대학교 수의과대학 생체안전성연구소) ;
  • 김인식 (전북대학교 수의과대학 생체안전성연구소)
  • Accepted : 2003.11.20
  • Published : 2003.12.25
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Abstract

Changes in the rat testis interstitium from birth to adulthood were studied using Sprague Dawley rats of 1, 7, 14, 21, 28, 40, 60, and 90 days of age to investigate Leydig cell differentiation. In addition, serum testosterone concentrations and luteinizing hormone stimulated (LH; 100 ng/ml) testosterone secretory capacity per testis in vitro were determined via radioimmunoassay. Fetal Leydig cells were present in rat testes from birth to 21 days, and they were only steroidogenic cells in the testis at days 1 and 7. The average volume of a fetal Leydig cell and the absolute volume of fetal Leydig cell per testis were similar at all ages of experimental groups except at day 21 when lower values were observed for both parameters. The number of fetal Leydig cells per testis remained constant from birth through 21 days. Adult Leydig cells were recognized at day 14 and their absolute volume and number per testis increased linearly from 14 to 90 days. The average volume of an adult Leydig cell increased significantly with age and reached maximum size by 60 days of age where the volume was nearly three times bigger than that of at day 14. Total testosterone production per testis in vitro and serum testosterone concentrations were not significantly different at day 1 compared with 7, 14, and 21 days of age. Significant increases were observed at days 40 and 60. Values at days 60 and 90 were not significantly different.

Keywords

References

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