Korean Journal of Veterinary Research (대한수의학회지)

The Korean Society of Veterinary Science (대한수의학회)
권호 표지

Expression and localization of endothelial and inducible nitric oxide synthase in bovine uterus

소 자궁에서 endothelial nitric oxide synthase(NOS) 및 inducible NOS의 발현

  • Lee, Yongduk (Department of Veterinary Medicine, College of Agriculture and Life Sciences, Cheju National University) ;
  • Kim, Seungjoon (Department of Veterinary Medicine, College of Agriculture and Life Sciences, Cheju National University) ;
  • Moon, Changjong (Department of Veterinary Medicine, College of Agriculture and Life Sciences, Cheju National University) ;
  • Shin, Taekyun (Department of Veterinary Medicine, College of Agriculture and Life Sciences, Cheju National University)
  • 이용덕 (제주대학교 농업생명과학대학 수의학과) ;
  • 김승준 (제주대학교 농업생명과학대학 수의학과) ;
  • 문창종 (제주대학교 농업생명과학대학 수의학과) ;
  • 신태균 (제주대학교 농업생명과학대학 수의학과)
  • Accepted : 2003.11.20
  • Published : 2003.12.25
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Abstract

Nitric oxide synthase (NOS) has been reported in uterus. We examined the expression of the NOS isoforms, constitutive endothelial (eNOS) and inducible NOS (iNOS), in bovine uterus by immunohistochemistry. eNOS immunoreactivity was localized predominantly to the endothelial cells that line uterine microvessels and to endometrial glandular epithelial cells, but was barely detectable in endometrial stromal cells. iNOS immunostaining was detected in glandular epithelial and stromal cells in the endometrium and in the endothelial cells of myometrial blood vessels. These findings suggest that both eNOS and iNOS may play important roles in the physiology of the uterus, possibly by generating NO.

Keywords

References

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