Korean Journal of Acupuncture

Society for Meridian and Acupoint (경락경혈학회)
권호 표지

The Effects of Mori Folium herbal acupuncture at St36 on ovalbumin-induced asthma in C57BL mouse

상엽약침(桑葉藥鍼)의 천식억제효과(喘息抑制效果)에 대한 실험적 연구

  • Shin, Sung-Chan (Dept. of Acupuncture & Moxibustion, College of Oriental Medicine, Daejeon University) ;
  • Kim, Young-Il (Dept. of Acupuncture & Moxibustion, College of Oriental Medicine, Daejeon University) ;
  • Hong, Kwon-Eui (Dept. of Acupuncture & Moxibustion, College of Oriental Medicine, Daejeon University) ;
  • Yim, Yun-Kyoung (Dept. of Meridian & Acupoint, College of Oriental Medicine, Daejeon University) ;
  • Lee, Hyun (Dept. of Acupuncture & Moxibustion, College of Oriental Medicine, Daejeon University) ;
  • Lee, Byung-Ryul (Dept. of Acupuncture & Moxibustion, College of Oriental Medicine, Daejeon University)
  • 신성찬 (대전대학교 한의과대학 침구학교실) ;
  • 김영일 (대전대학교 한의과대학 침구학교실) ;
  • 홍권의 (대전대학교 한의과대학 침구학교실) ;
  • 임윤경 (대전대학교 한의과대학 경혈학교실) ;
  • 이현 (대전대학교 한의과대학 침구학교실) ;
  • 이병렬 (대전대학교 한의과대학 침구학교실)
  • Published : 2004.09.27
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Abstract

Objective : The aim of this study was to investigate the effect of Mori Folium herbal acupuncture at St36 on ovalbumin-induced asthma in mice. Methods : C57BL/6 mice were sensitized and challenged with OVA (ovalbumin) for 12 weeks (once a week) Two experimental groups were treated with different concentrations (1%, 0.1%) of Mori Folium herbal acupuncture at Chok-samni (St36) for the later 8 weeks (3times/week). Result : 1. Lung weight of the mice group treated with Mori Folium herbal acupuncture decreased significantly compared with that of control group. 2. Total Leukocytes in BALF of the mice group treated with Mori Folium herbal acupuncture decreased significantly compared with those of control group. 3. The number of Eosinophils in BALF of the mice group treated with Mori Folium herbal acupuncture decreased significantly compared with that of control group. 4. The number of $Gr-1^+/CD11b,\;CCR3^+,\;CD4^+,\;CD8^+,\;CD3e^+/CD69^+,\;IgE^+/B220^+$ cells in the lungs of the mice group treated with Mori Folium herbal acupuncture decreased significantly compared with that of control group. 5. The concentration of IgE, IL-13, IL-4 in serum of the mice group treated with Mori Folium herbal acupuncture decreased significantly compared with that of control group. 6. The concentration of IL-4 in BALF of the mice group treated with Mori Folium herbal acupuncture decreased significantly compared with that of control group. Conclusion : We conclude that Mori Folium herbal acupuncture is effective on OVA-induced asthma of C57BL/6 mouse.

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