당분취의 식물화학적 성분연구

Phytochemical Constituents of Saussurea nutans Nakai

  • 발행 : 2004.03.30

초록

Seven terpenoids, trans-phytol (1), ${\alpha}-spinasterol$ (2),${\beta}-sitosterol$ (3), oleanolic acid (4), traxasterol (5), ${\alpha}-spinasterol\;3-O-{\beta}-D-glucopyranoside$ (8), ${\beta}-spinasterol\;3-O-{\beta}-D-glucopyranoside$ (9), and three glycerides, 3-O-(9Z, 12Z, 15Z-octadecatrienoyl) glycerol (6), 3-O-(9Z, 12Z-octadecadienoyl) glycerol (7), 1, 2-O-(9Z, 12Z, 15Z-dioctadecatrienoyl)-3-O-${\beta}$- D-galactopyranosyl glycerol (10) were isolated from n-hexane fraction of the aerial parts of Saussurea nutans which was used as Korean traditional medicine to σeat rheumatic arthritis and dysmenorrhea. Their structures were established by chemical and spectroscopic methods.

키워드

참고문헌

  1. 이창복(1997) 대한식물도감, 775. 향문사, 서울
  2. Duan, H., Takaishi, Y., Momota, H., Ohmoto, Y., and Taki, T.(2002) Immunosuppressive constituents from Saussureamedusa. Phytochemistry 59: 85-90 https://doi.org/10.1016/S0031-9422(01)00429-0
  3. Li, Y. and Jia, Z. J. (1989) Guaianolides from Saussureainvolucrata. Phytochemistry 28: 3395-3397 https://doi.org/10.1016/0031-9422(89)80354-1
  4. Goodman, R. A., Oldfield, E., and Allerhand, A. (1973)Assignments in the Natural-Abundance Carbon-13 NuclearMagnetic Resonance Spectrum of Chlorophyll a and a Studyof Segmental Motion in Neat Phytol. J. Am. Chem. Soc. 95:7553-7558 https://doi.org/10.1021/ja00804a003
  5. Sims, J. J. and Pettus, J. A. (1976) Isolation of free cis andtrans-Phytol from the red Alga Gracilaria andersoniana.Phytochemistry 15: 1076-1077 https://doi.org/10.1016/S0031-9422(00)84413-1
  6. Furuya, T., Orihara, Y., and Hayashi, C. (1987) Triterpenoidsfrom Eucalyptus periniana cultured cells. Phytochemistry 26:715-719 https://doi.org/10.1016/S0031-9422(00)84771-8
  7. Goad, L. J. and Akihisa T. (1997) Analysis of sterols, 388.Blackie Academic & Professional, Chapman Hall, London
  8. Mahato, S. B. and Kundu, A. P. (1994) $^{13}C$ NMR spectra ofpentacyclic triterpenoids-a complilation and some salientfeatures. Phytochemistry 37: 1517-1575 https://doi.org/10.1016/S0031-9422(00)89569-2
  9. Ahmad, V. U. and Rahman, A. U. (1994) Handbook ofnatural products data; volumn 2 Pentacyclic triterpenoids,Ill. Elsevier Science, Amsterdam
  10. Tanaka, R. and Matsunaga, S. (1988) Triterpene constituentsfrom Euphorbia supina. Phytochemistry 27: 3579-3584 https://doi.org/10.1016/0031-9422(88)80772-6
  11. Anjaneyulu, V., Ravi, K., Prasad, K. H., and Connolly, J. D. (1989) Triterpenoids from Mangifera indica. Phytochemistry28: 1471-1477 https://doi.org/10.1016/S0031-9422(00)97767-7
  12. Jung, C. M., Kwon, H. C., Choi, S. Z., Lee, J. H., Lee, D. J.,Ryu, S. N., and Lee, K. R. (2000) Phytochemicalconstituents of Ainsliaea acerifolia. Kor. J. Pharmacogn. 31:125-129
  13. Iida, T., Ishikawa, T., Tamura, T., and Matumoto, T. (1980)Carbon-13 nuclear magnetic resonance spectroscopicevidence of chondrillasterol isolated from ground seed oil.Yakugaku 29: 345-346
  14. Gohar, A. A., Olemy, M. M., Sattar, E. A., Said, M., andNiwa, M. (2000) Cardenolides and -sitosterol glucoside fromPergularia tomentosa L. Nat. Prod. Sci. 6: 142-146
  15. Jung, J. H., Lee, H. K., and Kang, S. S. (1996) Diacyl-glycerylgalactosides from Arisaema amurense.Phytochemistry 42: 447-452 https://doi.org/10.1016/0031-9422(95)00929-9
  16. Kobayashi, M., Hayashi, K., Kawazoe, K., and Kitagawa, I.(1992) Marine Natural Products. . Heterosigma-glycolipid I,Ⅱ, Ⅲ, and Ⅳ, Four Diacylglyceroglycolipids Possessing $\omega$3-Polyunsaturated Fatty Acid Residues from the Raphido-phycean Dinoflagellate Heterosigma akashiwo. Chem.Pharm. Bull. 40: 1404-1410 https://doi.org/10.1248/cpb.40.1404
  17. Dey, P. M. and Harborne, J. B. (1990) Methods in PlantBiochemistry (Vol. 4), 72 Academic Press, London