Korean Journal of Pharmacognosy (생약학회지)

The Korean Society of Pharmacognosy (한국생약학회)
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Glutathione S-transferase Activity and Hyaluronidase Inhibitory Effect of Medicinal Plants

생약의 Glutathione S-transferase 활성과 Hyaluronidase 저해효과

  • Lee, Eun-Hee (Department of Bio-Industry and Technology, Sangji University) ;
  • Cho, Jae-Yong (Department of Bio-Industry and Technology, Sangji University) ;
  • Cha, Bae-Cheon (Department of Bio-Industry and Technology, Sangji University)
  • 이은희 (상지대학교 생명자원과학대학 생명산업학과) ;
  • 조재용 (상지대학교 생명자원과학대학 생명산업학과) ;
  • 차배천 (상지대학교 생명자원과학대학 생명산업학과)
  • Published : 2004.09.30
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Abstract

This study was carried out to evaluate glutathione S-transferase (GST) activity and hyaluronidase inhibitory effect of medicinal plants. The EtOH extracts of 20 species plants were tested. As the result, Acorus gramineus and Pueraria lobata exhibited GST activity. On the continuous experiment, the n-BuOH fraction of Acorus gramineus and the $H_2O$ fraction of Pueraria lobata showed the elevation of GST activity. On the experiment of hyaluronidase inhibitory effect, Acorus gramineus exhibited a potent inhibitory activity. These results suggest that the extract of Acorus gramineus can be applicable for the development of a new anti-inflammatory agent.

Keywords

References

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