Applied Biological Chemistry

The Korean Society for Applied Biological Chemistry (한국응용생명화학회)
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Isolation and Identification of Antioxidant Flavonoids from Salicornia herbacea L.

퉁퉁마디에서 항산화 물질의 분리 및 동정

  • Kim, Kwan-Su (School of Biotechnology and Resources, Mokpo National University) ;
  • Park, Si-Hyung (School of Biotechnology and Resources, Mokpo National University)
  • 김관수 (목포대학교 생물산업학부 생약자원) ;
  • 박시형 (목포대학교 생물산업학부 생약자원)
  • Published : 2004.03.31
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Abstract

Two flavonoids were isolated from the aerial parts of Salicornia herbacea L. by column chromatography. The structures of the flavonoid compound 1 and 2 were identified as quercetin $3-O-{\beta}-D-glucopyranoside$ and isorhamnetin $3-O-{\beta}-D-glucopyranoside$, respectively. The antioxidant activity of compound 1 was similar to those of quercetin and rutin, and the activity of compound 2, which contained methoxyl group at flavonoid B-ring, was lower than that of compound 1. The two compounds 1 and 2 were the first to be reported in this plant.

퉁퉁마디(Salicornia herbacea L.) MeOH 추출물로부터 2종의 화합물을 분리하고 DPPH 라디칼 소거 반응을 이용하여 항산화 활성을 측정하였다. UV-Vis 흡수 스펙트럼과 MS와 NMR스펙트럼으로부터 물질 1과 2는 quercetin $3-O-{\beta}-D-glucopyranoside$와 isorhamnetin $3-O-{\beta}-D-glucopyranoside$로 동정하였다. 분리된 화합물 1과 2의 DPPH 라디칼 소거 활성을 측정한 결과 1은 quercetin, rutin과 비슷한 활성을 나타내었으며, B-ring의 hydroxyl 그룹이 methoxyl 그룹으로 치환된 화합물 2는 이보다 약한 활성을 나타내었다. 화합물 1과 2는 퉁퉁마디에서는 처음으로 분리되어 보고되는 화합물이다.

Keywords

References

  1. Lee, T. B. (1989) In Illustrated Ftora of Korea. (4th ed.) Hyang Mun Sa, Seoul
  2. Min, J. G., Lee, D. S., Kim, T. J., Park, J. H., Cho and T. Y, Park, D. I. (2002) Chemical composition of Saticomia herbacea L. J. Food Sci. Nutr. 7, 105-107 https://doi.org/10.3746/jfn.2002.7.1.105
  3. Jo, Y. C., Ahn, J. H., Chon, S. M., Lee, K. S., Bae, T. J. and Kang, D. S. (2002) Studies on pharmacological effects of glasswort (Salicornia herbace.a L.). Korean J. Med. Crop Sci. 10, 93-99
  4. Min, J. G., Son, K. T, Kim, J. H., Kim, T. J. and Park, J. H (2002) Physiological and functional properties of Salicomia herbacea leaf extracts. Nutraceut. Food 7, 261-264 https://doi.org/10.3746/jfn.2002.7.3.261
  5. Dufall, K. G., Ngadjui, B. T, Simeon, K. R, Abegaz, B. M and Croft, K. D. (2003) Antioxidant activity of prenylated Havonoids from the west african medicinal plant Dorstenia mannii. J. Ethnophannacol. 87, 67-72 https://doi.org/10.1016/S0378-8741(03)00108-9
  6. Day, A. J., Bao, Y, Morgan, R. A. and Williamson, G. (2000) Conjugation position of quercetin glucuronides and effects on biological activity. Free Rad. Biol. Med. 29, 1234-1243 https://doi.org/10.1016/S0891-5849(00)00416-0