Advances in Traditional Medicine

Kyung Hee Oriental Medicine Research Center (경희대학교 융합한의과학연구소)
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Antidiarrhoeal activity of Arque-Ajeeb, a compound formulation of Unani medicine in rats

  • Khan, M. Aleem (Department of Ilmul Advia (Pharmacology), Faculty of Unani Medicine, Aligarh Muslim University) ;
  • Khan, Naeem A. (Department of Ilmul Advia (Pharmacology), Faculty of Unani Medicine, Aligarh Muslim University) ;
  • Qasmi, Iqbal A. (Department of Ilmul Advia (Pharmacology), Faculty of Unani Medicine, Aligarh Muslim University) ;
  • Ahmad, Ghufran (Department of Ilmul Advia (Pharmacology), Faculty of Unani Medicine, Aligarh Muslim University) ;
  • Zafar, Shadab (Medical Officer-in-Charge, Unani Dispensary, Municipal Corporation of Delhi, Jhatikra)
  • Published : 2004.06.30
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Abstract

The efficacy of Arque-Ajeeb (AA), a compound formulation of Unani medicine was investigated for antidiarrhoeal activity against barium sulphate-induced gut motility and castor oil-induced diarrhoea in rats. The control, standard and test groups of experimental animals were administered with distilled water (p.o.), lomotil (p.o.) and AA (0.007 ml and 0.014 ml/100 g, p.o.) respectively. Barium sulphate and castor oil were administered after 15 and 60 min respectively in each group of first and second experiment. The distance traveled by barium sulphate in small intestine was measured after 15 and 30 min of barium sulphate administration and diarrhoea was observed every 30-min for six hour after castor oil administration. Oral administration of AA caused significant reduction in diarrhoea. AA may have the potential to reduce the diarrhoea in rats.

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References

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