NECROSIS OF A PAROTID GLAND PLEOMORPHIC ADENOMA : A CASE REPORT

이하선 다형성 선종의 괴사

  • Ryu, Sun-Youl (Department of Oral and Maxillofacial Surgery, College of Dentistry, Dental Science Research Institute, Chonnam National University) ;
  • Baek, Sung (Department of Oral and Maxillofacial Surgery, College of Dentistry, Dental Science Research Institute, Chonnam National University) ;
  • Park, Hong-Ju (Department of Oral and Maxillofacial Surgery, College of Dentistry, Dental Science Research Institute, Chonnam National University) ;
  • Choi, Hong-Ran (Department of Oral Pathology, College of Dentistry, Dental Science Research Institute, Chonnam National University)
  • 유선열 (전남대학교 치과대학 구강악안면외과학교실, 전남대학교 치의학연구소) ;
  • 백승 (전남대학교 치과대학 구강악안면외과학교실, 전남대학교 치의학연구소) ;
  • 박홍주 (전남대학교 치과대학 구강악안면외과학교실, 전남대학교 치의학연구소) ;
  • 최홍란 (전남대학교 치과대학 구강병리학교실, 전남대학교 치의학연구소)
  • Published : 2004.04.30

Abstract

Pleomorphic adenoma is the most common neoplasm of the parotid gland, generally presenting as a slowly growing, firm, well-circumscribed, painless nodule. It is often difficult to separate into benign and malignant categories because its bland histomorphologic and cytologic features. This tumor can be rarely associated with cystic change, hemorrhagic necrosis, or spontaneous infarction. Necrosis of lesional tissue may be associated with malignant transformation, particularly in a pleomorphic adenoma. We report a case of 50-year-old woman presented with a enlarging right parotid mass. Computed tomographic scan demonstrated a right superficial lobe mass with ill-defined border. The preoperative fine needle aspiration yielded necrotic debris and atypical squamous elements that were thought to be compatible with high degree of mucoepidermoid carcinoma. A total parotidectomy with intraoperative frozen section revealed extensive necrosis and diagnosed as malignant tumor. This tumor was finally diagnosed as a pleomorphic adenoma with necrosis on permanent sections. Caution should be exercised in evaluation of the parotid neoplasms with central necrosis to avoid misdiagnosis of such lesions as malignancy.

본 증례는 우측 이하선에 종물을 가진 50세 여자 환자에서 술전에 시행한 세침흡인검사와 전산화단층촬영 소견 및 술중에 시행한 동결생검에서 괴사소견으로 인해 점액표피양암종으로 진단되어 우측 이하선 전적출술과 경부청소술 등을 시행하였으나 수술 후 조직병리학적 검사에서 괴사를 동반한 다형성 선종으로 최종 진단되었다. 괴사를 동반한 다형성 선종에서 보이는 편평 상피세포는 점액표피양암종에서 나타나는 편평세포의 특징으로 오진할 수 있으므로 주의해야 한다. 본 증례는 악성종양으로 잘못 진단할 수 있는 다형성 선종의 괴사와 조직병리학적 특징들을 이해함으로써 임상의사들의 오진 가능성을 예방하고 다형성 선종의 진단과 치료에 주의해야 함을 시사한다.

Keywords

References

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