Korean Journal of Food Science and Technology (한국식품과학회지)

Korean Society of Food Science and Technology (한국식품과학회)
권호 표지

Estimated Dietary Intake of Sodium Saccharin and Acesulfame Potassium in Koreans

식품 중 사카린나트륨, 아세설팜칼륨의 섭취량에 관한 연구

  • Kim, Hee-Yun (Center for Food Safety Evaluation, Korea Food and Drug Administration) ;
  • Yoon, Hae-Jung (Center for Food Safety Evaluation, Korea Food and Drug Administration) ;
  • Hong, Ki-Hyoung (Center for Food Standard Evaluation, Korea Food and Drug Administration) ;
  • Choi, Jang-Duck (Office of Analysis and Evaluation, Korea Food and Drug Administration) ;
  • Park, Sung-Kwan (Center for Food Standard Evaluation, Korea Food and Drug Administration) ;
  • Park, Hui-Og (Food and Drug Department, Chosun University) ;
  • Jin, Myeong-Sig (Food and Drug Department, Chosun University) ;
  • Choi, Woo-Jeong (Center for Food Safety Evaluation, Korea Food and Drug Administration) ;
  • Park, Sun-Young (Center for Food Safety Evaluation, Korea Food and Drug Administration) ;
  • Lee, Kyoung-Joo (Center for Food Safety Evaluation, Korea Food and Drug Administration) ;
  • Lee, Chul-Won (Center for Food Safety Evaluation, Korea Food and Drug Administration)
  • 김희연 (식품의약품안전청 식품안전평가부) ;
  • 윤혜정 (식품의약품안전청 식품안전평가부) ;
  • 홍기형 (식품의약품안전청 식품규격평가부) ;
  • 최장덕 (식품의약품안전청 시험분석담당관실) ;
  • 박성관 (식품의약품안전청 식품규격평가부) ;
  • 박희옥 (조선대학교 식품의약학과) ;
  • 진명식 (조선대학교 식품의약학과) ;
  • 최우정 (식품의약품안전청 식품안전평가부) ;
  • 박선영 (식품의약품안전청 식품안전평가부) ;
  • 이경주 (식품의약품안전청 식품안전평가부) ;
  • 이철원 (식품의약품안전청 식품안전평가부)
  • Published : 2004.10.31
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Abstract

Mean concentration of 2 artificial sweeteners, sodium saccharin and acesulfame K, in food samples and their daily intakes were estimated. Among 755 food samples, 57 contained these artificial sweeteners. Contribution rate to total estimated daily intake (%) of artificial sweeteners in food categories were high in danmooji for sodium saccharin and ice cream for acesulfame K. Total estimated daily intakes $({\Sigma}EDI)$ for different age groups were high in 30-49 year-old group for sodium saccharin and 13-19 year-old group for acesulfame K. Total estimated daily intakes $({\Sigma}EDI)$ of men and women were 5.91 and 4.89 mg/man/day, respectively. Total estimated daily intakes $({\Sigma}EDI)$ based on mean body weight of 55 kg were 4.13 and 1.25 mg/man/day for sodium saccharin and acesulfame K, respectively. These values ranged within 0.2-1.5% of acceptable daily intake (ADI) evaluated by FAO/WHO and 1.2-13.5% of theoretical maximum daily intake (TMDI), and, therefore, judged to be safe.

시중에서 유통되고 있는 제품 중 사카린나트륨 및 아세설팜칼륨이 사용 가능한 대상식품인 빵 또는 떡류, 김치류, 음료류, 어육가공품, 건과류, 아이스크림류, 잼류 및 발효유류 등 46종 755품목을 대상으로 인공감미료 2종에 대한 사용실태를 파악하고 식이를 통해 실제 섭취되는 인공감미료의 총 섭취량을 조사하여 FAO/WHO의 ADI와 비교 검토함으로서 인공감미료의 실제 섭취량과 ADI간 안전수준평가 및 사용기준 개정시 기초 자료로 활용하고자 수행하였다. 따라서 분석된 결과를 기초로 식품유형별, 연령대별, 성별 및 인공감미료별 사용실태를 파악하고 국민영양조사자료에 근거하여 대상식품의 유형과 연령에 따른 인공감미료별 1인 1일당 추정섭취량을 산출하였으며 FAO/ WHO에서 설정한 ADI와 비교 검토한 결과, 총 검사건수 755건 중 57건의 인공감미료가 검출되어 7.6%의 검출율을 나타내었으며 인공감미료별 검출건수와 검출율은 각각 사카린나트륨 49건(6.5%) 및 아세설팜칼륨 11건(1.5%)으로 나타났다. 또한, 대상식품별 일일추정섭취량을 산출한 결과 사카린나트륨은 단무지에서, 아세설팜칼륨은 아이스크림에서 가장 높은 것으로 나 타났다. 연령별 ${\Sigma}EDI$는 1.89-4.91 mg/man/day의 범위로 13-19세에서 인공감미료 섭취가 가장 많았으며 65세 이상에서 가장 낮았다. 또한 각 인공감미료를 연령대별로 보면 사카린나트륨은 30-49세, 아세설팜칼륨은 13-19세에서 가장 섭취량이 많은 것으로 나타났다. 성별 ${\Sigma}EDI$는 남성은 5.91 mg/man/day, 여성은 4.89 mg/man/day으로 나타났다 국민영양조사표 등의 식품별 1인 1일당 섭취량과 인공감미료별 평균검출농도로부터 일일추정 섭취량을 산출하였을 때, 인공감미료별 ${\Sigma}EDI$는 사카린나트륨 4.13 mg/man/day, 아세설팜칼륨 1.25 mg/man/day로 각 인공감미료의 ADI를 국민평균체중 55 kg으로 환산한 275-825 mg/man/day와 비교하였을 때 매우 낮은 수치를 나타내었으며 이 결과는 ADI 대비 0.2-1.5% 수준이었고 사용가능 대상식품의 이론적 TMDI의 1.2-13.5%의 수준으로 사용대상식품을 통한 인공감미료의 섭취는 안전하다고 판단된다.

Keywords

References

  1. Gibney MJ. Dietary intake methods for estimating food additive intake. Regulatory Toxicol. Pharmacol. 30: 31-33 (1999) https://doi.org/10.1006/rtph.1999.1323
  2. Yukimasa M, Yuka K, Takashi H, Nobumi A, Masanori S, Yoshio I. Preparation an characterization of sulfite adducts. Toxicol. Environ. Health. Jpn. 41: 440-446 (1995) https://doi.org/10.1248/jhs1956.41.440
  3. Sumiko T, Tadashi S, Kenji I, Takeo K, Mieko K, Motohiro N, Hiromichi H, Toshinobu F, Hiroyuki K, Munehiko G, Yoshio S, Kiyoshi S, Kakuyuki O, Hiroshi M, Hisanori U, Teruo S, Yoshio I. Daily intake of non-naturally occurring chemically synthesized food additives from the processed foods purchased in Japan. J. Food Hyg. Soc. Jpn. 36: 93-101 (1995) https://doi.org/10.3358/shokueishi.36.93
  4. Sumiko T, Tadashi S, Motohiro N, Yoshinobu F, Hiroyuki K, Munehiko G, Yoshio S, Yasuko M, Zensho O, Minoru S, Kazuo N, Shigeru M, Shuichi E, Yayoi S, Hisanori U, Teruo S, Yoshio I. Estimation of daily intake of chemically synthesized natural food additives from processed foods in Japan. J. Food Hyg. Soc. Jpn. 37: 308-318 (1996) https://doi.org/10.3358/shokueishi.37.5_308
  5. Sumiko T, Kaori F, Masa K, Tadashi S, Sachiko UH, Miyuki F, Noboru K, Yoshiko O, Kazuya F, Hiroshi S, Yoshio I. Naturally occurring of sulfites in raw and processed foods. J. Food Hyg. Soc. Jpn. 34: 303-313 (1993) https://doi.org/10.3358/shokueishi.34.303
  6. Sumiko T, Masako K, Yukihiro M, Tadashi S, Noboru K, Kazuya F, Kazuko W, Sachiko UH, Shigeaki I, Kazuya F, Hiroshi S, Yoshio I. Naturally occurring of nitrite existing in various raw and processed foods. J. Food Hyg. Soc. Jpn. 34: 294-302 (1993) https://doi.org/10.3358/shokueishi.34.294
  7. Sumiko T, Tadashi S, Nobutake U, Tateo K, Hiroshi S, Sachioko UH, Junko M, Noboru K, Yoshio I. Naturally occurring of orthophosphate ion in various rqu and processed foods by ion chromatography. J. Food Hyg. Soc. Jpn. 35: 56-65 (1994) https://doi.org/10.3358/shokueishi.35.56
  8. Sumiko T, Tadashi S, Koichiro O, Koji T, Tasuchi F, Yoshio I. Preparation of sample solution using pronase treatment for determination of food coal-tar dyes in foods. J. Food Hyg. Soc. Jpn.36: 68-76 (1994)
  9. Tomomi K, Tomoko Y, Yoshie T, Nastsuyo H, Yoshiko T, Miki F, Masanori S, Sumiko, T, Tadashi S, Yosio I. Studies on daily Intake of Food Coal-tar Dye in Japan. J. Food Chem. Jpn. 2: 16-23 (1995)
  10. Lee CW, Lee DS, Moon BS. A study on intakes of some food additives by Korean. Korean J. Food Hyg. 4: 1-20 (1989)
  11. Kim KS, Lee CW, Lee DS, Lee YJ, Yu SY, Kim YK, Lee JD, Moon BS, Shin MK. A study on intakes of some food additives by Korean (I) (DHA, BHA, BHT). Ann. Report NIH 22: 443-454 (1985)
  12. Kim KS, Lee CW, Lee DS, Lee YJ, Yu SY, Kim YK, Kim KN, Kim JH, Moon BS. A study on intakes of some food additives by Korean (II) (Benzoic acid, Sorbic acid, ρ-Hydroxybenzoate ester). Ann. Report NIH 23: 631-642 (1986)
  13. Kim KS, Lee CW, Lee DS, Lee YJ, Yu SY, Kim YK, Kim KN, Hong KH, Kim HJ, Moon BS. A study on intakes of some food additives by Korean (III) (Propionic acid, Sodium nitrite, Sodium sulfite (as $SO_2$)). Ann. Report NIH 24: 719-732 (1987)
  14. Lee CW, Kim BS, Kwak IS, Lee CH, Park SK, Huh SY, Ju SK, Kang KM, Park JS, Kim KS. A study on food additives from diet (Artificial sweeteners). Ann. Report KFDA 1: 67-74 (1997)
  15. Lee CH, Park SK, Yun HJ, Park JS, Lee JO. Estimation of daily intake of artificial sweetener and antioxidants in foods. Korean J. Food Sci. Technol. 32: 519-524 (2000)
  16. FAO/IPCS. Summary of Evaluations Performed by the Joint FAO/WHO Expert Committee Food Additives. JECFA, Rome, Italy (1994)
  17. Lee JO, Yun HJ, Lee CH, Park SK, Lee CW. A study for analytical method of synthetic color additives in foods (I). Ann. Report KFDA 2: 107-115 (1998)
  18. Lee JO, Kim SH, Yun HJ, Lee CH, Park SK, Park JS, Jung YH, Chae SY, Kim EJ, Lee CW. A study for analytical method of synthetic color additives in foods (II). Ann. Report KFDA 3: 129-148 (1999)
  19. JECFA. Safety evaluation of certain food additives. WHO Food Add. Series 42: 402-459 (1999)
  20. Kim HY, Yoon HJ, Hong KH, Lee CH, Park SK, Choi JM, Park SY, Lee KJ, Oh SJ, Kim MS, Park SM, Lee CW. A study on intake of artificial sweeteners in foods (I). Ann. Report KFDA 6:169-176 (2003)
  21. Ministry of health and welfare. Report on 2001 National Health and Nutrition Survey (Dietary Intake Survey). Korea Health Industry Development Institute, Seoul, Korea (2001)
  22. Hajimu I, Motohiro N, Yoshinobu F, Yoshio I, Takashi Y. Evaluation of the contents of BHA, BHT, propylene glycol, and sodium saccharin in foods and estimation of daily intake based on the results of official inspection in Japan in fiscal year 1994. J. Food Hyg. Soc. Jpn. 39: 89-100 (1998) https://doi.org/10.3358/shokueishi.39.89
  23. Shin KH, Lee YH, Lee YJ, Lee HD. A study on the food additives. (The simultaneous analysis of food colorants by HPLC). Ann. Report NIH 18: 377-381 (1981)
  24. Hajimu I, Takiko S, Yoko K, Yuiko T, Takashi Y, Motohiro N, Yoshinobu F. Estimation of antifungal agent concentrations allowed as food additives in food and their daily intake based on official inspection results in Japan in fiscal year 1996. J. Food Hyg. Soc. Jpn. 40: 407-416 (1999) https://doi.org/10.3358/shokueishi.40.5_407
  25. Hajimu I, Takiko S, Yoko K, Yuiko T, Takashi Y, Motohiro N, Yoshinobu F. Estimation of preservative concentrations in food and their daily intake based on official inspection results in Japan in fiscal year 1996. J. Food Hyg. Soc. Jpn. 40:246-258 (1999) https://doi.org/10.3358/shokueishi.40.3_246
  26. Kim HY, Lee YJ, Hong KH, Ha SC, An MS, Cho JS, Kim KS. Intake of food additives in foods by total diet. Food Sci. Technol. 30: 767-774 (1998)
  27. Leclercq C, Berardi D, Sorbillo MR, Lambe J. Intake of saccharin, aspartame, acesulfame K and cyclamate in Italian teenagers: present levels and projections. Food Add. Contam. 16: 99-109 (1999) https://doi.org/10.1080/026520399284145
  28. Renwick AG. Intake studies on low-calorie sweeteners: methods, results and comparisons. In: Intake Studies-Lessons Learnt. Corti A (ed). International Sweeteners Association, Brussels, Belgium. pp. 79-97 (1995)
  29. Hulshof KFAM, Bouman M. Use of various types of sweeteners in different population groups. In: 1992 Dutch National Food Consumption Survey. Hulshof KFAM, Bouman M (eds). TNO Nutrition and Food Research Institute, Bonn, Germany (1995)
  30. Hinson AL, Nicol WM. Monitoring sweetener consumption in Great Britain. Food Add. Contam. 9: 669-681 (1992) https://doi.org/10.1080/02652039209374122