The Effects of TENS and cold application on secondary thermal hyperalgesia in rats induced by muscle pain

근통증이 유발된 흰쥐에 있어 TENS와 냉적용이 이차성 열 통각과민에 미치는 영향

  • Chae Yun-Won (Department of Physical Therapy, Kwangju Health College) ;
  • Kim Sang-Yub (Department of Physical Therapy, Kwangju Health College) ;
  • Kim Jin-sang (Department of Physical Therapy, College of Rehabilitation Science, Daegu University) ;
  • Park Rae-joon (Department of Physical Therapy, College of Rehabilitation Science, Daegu University) ;
  • Gu Hyun-mo (Department of Physical Therapy, Graduate School of Rehabilitation, Daegu University) ;
  • Lim Chang hun (Department of Physical Therapy, Graduate School of Rehabilitation, Daegu University)
  • 채윤원 (광주보건대학 물리치료과) ;
  • 김상엽 (광주보건대학 물리치료과) ;
  • 김진상 (대구대학교 재활과학대학 물리치료학과) ;
  • 박래준 (대구대학교 재활과학대학 물리치료학과) ;
  • 구현모 (대구대학교 대학원 재활과학과 물리치료) ;
  • 임창훈 (대구대학교 대학원 재활과학과 물리치료)
  • Published : 2004.06.01

Abstract

The aim of this study was to investigate the effects of TENS and cold application on secondary thermal hyperalgesia in rats induced by muscle pain. Muscle pain was induced in male Sprague-Dowley rats by intra-muscular injection of gastrocnemius with $3\%$ carrageenan. The paw withdrawal latency(PWL) and tail flick test(TFT) to heat were used to detect secodary thermal hyperalgesia induced by the muscle pain. PWL and TFT were quantified before and 4, 10, and 24 h after induction of muscle pain and after application of TENS(100Hz, $100{\mu}s$, sensory intensity) and cold($4^{\circ}C$). TENS and cold significantly reduced the PWL and TFT to heat stimuli when compared with controls receiving no TENS and cold(p<.05). These results suggested that application of TENS and cold attributed to decrease secodary thermal hyperalgesia in rat induced by muscle pain.

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