The Journal of Korean Physical Therapy

The Korean Society of Physical Therapy (대한물리치료학회)
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The Effect of Microcurrent Stimulation on Immediately Early Gene in Pain Induced Model

실험적 통증유발 모델에서 조기발현 유전자에 대한 미세전류자극의 효과

  • Kim Gye-Yeop (Department of Physical Therapy, College of Oriental Medicine, Dongshin University) ;
  • Kim Tae-Youl (Department of Physical Therapy, College of Oriental Medicine, Dongshin University) ;
  • Oh Myung-Hwa (Department of Physical Therapy, College of Oriental Medicine, Dongshin University) ;
  • Kim Sun-Eun (Department of Physical Therapy, College of Oriental Medicine, Dongshin University) ;
  • Cheong Mee-Sun (Department of Physical Therapy, College of Oriental Medicine, Dongshin University) ;
  • Suh Young-Sook (Department of Nursing, College of Oriental Medicine, Dongshin University)
  • 김계엽 (동신대학교 한의과대학 물리치료학과) ;
  • 김태열 (동신대학교 한의과대학 물리치료학과) ;
  • 오명화 (동신대학교 한의과대학 물리치료학과) ;
  • 김선은 (동신대학교 한의과대학 물리치료학과) ;
  • 정미선 (동신대학교 한의과대학 물리치료학과) ;
  • 서영숙 (동신대학교 한의과대학 간호학과)
  • Published : 2004.09.01
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Abstract

The purpose of study is that we will observe the change of c-fos with the immunohistochemistry method and then we will study the effect of micro current stimulation following the frequency after inducing pain to rats with capsaicin. Rat were classified to SD and they have growed for 8 weeks. We classify to four groups, ordinal group is used in experiment I, the group which we induce pain is used in experiment II, the application group which we induce pain and then the high frequency micro current stimulation is used in experiment III, the application group which we induce pain and then the low frequency micro current stimulation is used in experiment IV, we get the following result. Compare with experiment II, experiment III, and experiment IV from acute pain modal in the immunohistochemistry experiment which has c-fos protein as an antigen, c-fos immunoreactive positive neurons significantly after induced pain for two hours(p<0.001). According to these results, from rats induced pain, micro current stimulation effect to reducing pain, but following frequency micro current stimulation theraphy isn't different from immunoreactive c-fos

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