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Effect of Polyphenol Compound from Korean Pear(Pyrus pyrifolia Nakai) on Lipid Metabolism

한국산 배로부터 분리한 Polyphenol 분획물이 지질대사에 미치는 영향

  • Choi, Hee-Jin (Dept. of Food Science and Technology, Yeungnam University) ;
  • Park, Jung-Hye (Dept. of Food Science and Technology, Yeungnam University) ;
  • Han, Ho-Seok (Dept. of Food Science and Technology, Yeungnam University) ;
  • Son, Jun-Ho (Dept. of Food Science and Technology, Yeungnam University) ;
  • Son, Kyu-Mok (Division of Food Science, Changwon Junior College) ;
  • Bae, Jong-Ho (Dept. of Confectionary Decoration, Daegu Mirae College) ;
  • Choi, Chung (Dept. of Food Science and Technology, Yeungnam University)
  • 최희진 (영남대학교 생물산업공학부) ;
  • 박정혜 (영남대학교 생물산업공학부) ;
  • 한호석 (영남대학교 생물산업공학부) ;
  • 손준호 (영남대학교 생물산업공학부) ;
  • 손규목 (창원전문대학 식품영양과) ;
  • 배종호 (대구미래대학 제과데코레이션과) ;
  • 최청 (영남대학교 생물산업공학부)
  • Published : 2004.02.01

Abstract

This study was conducted to investigate the effects of the polyphenol fraction isolated from pear on the reduction of fat accumulation in rats fed on high fat diet for 5 weeks, which was examined by analyzing the lipid composition in serum, liver and feces biochemically. It was shown that the levels of total lipid and total cholesterol in serum were remarkably reduced in polyphenol fraction supplemented group as compared with the control group. The levels of total lipid and triglyceride were also significantly lower in polyphenol group than control group. The contents of total lipid, total cholesterol and triglyceride in feces were tended to be slightly increased in polyphenol group compared to control group. The total protein and albumin of polyphenol groups were lower compared to those of control group, which were not significant.

배로부터 polyphenol 화합물군을 분리 및 정제하여5주간 고지방식이를 한 후, 혈장 및 간장에서의 지질대사에 미치는 영향을 분석한 결과 혈장에서는 배의 polyphenol 화합물군 PR-II에서 총지질, 총콜레스테롤이 유의성 있게 감소하였다 또한 간장에서는 총지질, 중성지질이 대조군에 비해서 유의성 있는 결과가 나타났다 5주 동안 고지방 식이를 한 후 분변을 채취하여 총지질, 총콜레스테롤 및 중성지질을 측정한 결과 배에서 추출한 polyphenol화합물 군이 고지방식이만을 섭취시킨 대조군에 비해 다소 감소되는 경향을 보였다. 배의 polyphenol 화합물군을 섭취시킨 후 총단백질과 알부민 함량을 측정한 결과 대조군과 실험군에서 유의성 있는 차이는 나타나지 않았다.

Keywords

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