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Effect of Liquid. Culture of Coriolus versicolor on Lipid Metabolism, Protein Level and Enzyme Activities in Rats

운지버섯 균사체 배양액이 성장기 흰쥐의 지질대사, 단백질 농도 및 효소활성에 미치는 영향

  • 고진복 (신라대학교 생명과학과) ;
  • 최미애 (양산대학 식품가공제과제빵과)
  • Published : 2004.03.01

Abstract

The effects of liquid culture of Coriolus versicolor on the body weight gain, lipid metabolism, protein levels and enzyme activities were studied in growing male rats. Sprague-Dawley rats were divided into four groups; control group (C. versicolor free water), 10%, 20% or 30% C. versicolor groups (10%, 20% or 30% C. versicolor in water) according to the levels of C. versicolor supplementation. The rats were fed ad libitum each of the experimental beverage for 5 weeks. The body weight gain, food intake, food efficiency ratio, and organ weight of the all C. versicolor groups were similar to those of the control group. There were no differences in the concentrations of triglyceride, total cholesterol, HDL-cholesterol, total protein and albumin, and the activities of GOT, GPT, and alkaline phosphatase of the serum among the experimental groups. However, the atherogenic index of the 30% C. versicolor groups were significantly lower than those of the control group, and the serum HDL-cholesterol/total cholesterol ratio increased.

운지버섯의 균사체 배양액이 성장기 흰쥐의 영양생리에 미치는 영향을 관찰하고자 생후 7주령의 숫쥐를 대상으로 음료수에 10%, 20% 및 30%수준으로 운지버섯 균사체 배양액을 혼합하여 5주간 급여하고 성장률, 식이 섭취 량, 식이효율, 장기의 무게, 간과 혈청의 지질 농도, 혈청의 단백질 농도 및 효소 활성을 조사한 결과는 다음과 간다. 체중증가량, 식이섭취량, 식이효율 및 장기의 무게는 대조군과 운지버섯 음료군들이 비슷한 경향이었다. 간과 혈청의 중성지질과 콜레스테롤 농도 및 혈청의 HDL-콜레스테를 농도는 대조군과 운지버섯 음료군들이 비슷한 수준으로 나타났다. 혈청의 동맥경화지수는 대조군에 비해 30% 운지버섯 음료군이 유의하게 감소되었다. 혈청의 총 콜레스테롤에 대한 HDL-콜레스테롤의 비율은 대조군에 비해 30% 운지버섯 음료군이 유의하게 증가되었다. 혈청의 총 단백질, 알부민, 혈당, 혈색소, 칼슘, 무기인 및 마그네슘 등의 농도는 각 수준별 운지버섯 음료군이 대조군과 비슷한 농도로 운지 버섯 음료 섭취에 따른 영향은 나타나지 않았다. 혈청의 GPT, GOT 및 ALP 등의 활성도 운지 버섯 음료 섭취에 따른 영향은 나타나지 않았다. 이상의 결과로 보아 대조식이와 10%, 20% 및 30% 수준의 운지 버섯 음료 섭취에 의한 성장률, 간과 혈청의 콜레스테롤 및 중성지질 농도, 단백질 농도 및 효소 활성에는 영향을 받지 않는 것으로 나타났다. 30% 운지 버섯 섭취시 혈청의 동맥 경화지수를 낮추는 효과가 있고, 혈청의 총 콜레스테롤에 대한 HDL-콜레스테롤의 비율을 높여주는 효과가 있는 것으로 나타났다.

Keywords

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