DD1.5k, the Gene Preferentially Expressed in Bloodstream Isolates of Vancomycin-Resistant Enterococcus faecium

  • Kim, Seung-Han (Clinical Research Institute, The Catholic University of Korea) ;
  • Lee, Dong-Gun (Department of Internal Medicine, The Catholic University of Kore) ;
  • Yoo, Jin-Hong (Department of Internal Medicine, The Catholic University of Kore) ;
  • Park, Su-Mi (Department of Internal Medicine, The Catholic University of Kore) ;
  • Park, Jung-Hyun (Department of Internal Medicine, The Catholic University of Kore) ;
  • Shin, Wan-Shik (Department of Internal Medicine, The Catholic University of Kore) ;
  • Lee, Kyungwon (Department of Laboratory Medicine and Research Institute of Bacterial Resistance, Yonsei University College of Medicin) ;
  • Dongeun Yong (Department of Laboratory Medicine and Research Institute of Bacterial Resistance, Yonsei University College of Medicin) ;
  • Lee, Wee-Gyo (Department of Laboratory Medicine, Ajou University School of Medicine)
  • Published : 2004.06.01

Abstract

Vancomycin-resistant Enterococcus faecium (VREFM) is becoming a threatening pathogen. We identified a gene called DD1.5K by differential display-PCR, which was preferentially expressed in the bloodstream isolates of VREFM. Due to its amino acid similarity to transfer complex protein, trsE, and tissue-specific expression, this gene may be involved in virulence of VREFM.

Keywords

References

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