Journal of the Korean Ceramic Society (한국세라믹학회지)

The Korean Ceramic Society (한국세라믹학회)
권호 표지
DOI QR코드

DOI QR Code

Hybrid Coextrusion and Lamination Process for Macrochanneled Bioceramic Scaffolds

  • Koh, Young-Hag (School of Materials Science add Engineering, Seoul National University) ;
  • Bae, Chang-Jun (School of Materials Science add Engineering, Seoul National University) ;
  • Kim, Hyoun-Ee (School of Materials Science add Engineering, Seoul National University)
  • Published : 2004.07.01
Download PDF
⟨ Previous Next ⟩

Abstract

A hybrid coextrusion and lamination process has been developed to fabricate macrochanneled bioceramic scaffolds. This process was mainly composed of three steps (i.e., coextrusion of thermoplastic compound, lamination, and thermal treatment), forming unique pore channels in dense bioceramic body. Pore channels were formed by removing carbon black material, while calcium phosphate or Tetragonal Zirconia Polycrystals (TZP) with a calcium phosphate coating layer were used as dense body. Two kinds of pore structures were fabricated; that is, the pore channels were formed in uni- or three-directional array. Such macrochanneled bioceramic scaffolds exhibited the precisely controlled pore structure (pore size, porosity, and interconnection), offering excellent mechanical properties and cellular responses.

Keywords

References

  1. Clin. Orthop. Relat. Res. v.157 Calcium Phosphate Ceramics as Hard Tissue Prosthetics M. Jarcho
  2. Plast. Reconstr. Surg. v.83 Porous, Block HA as an Interpositional Bone Graft Substitute in Orthognatic Surgery H. M. Rosen https://doi.org/10.1097/00006534-198906000-00009
  3. Clin. Orthop. Relat. Res. v.248 Macroporous Calcium Phosphate Ceramic Performance in Human Spine Fusion N. Passuti;G. Daculsi;J. M. Rogez;S. Martin;J. V. Bainvel
  4. Nature(London) v.247 HA Formed from Coral Skeletal Carbonate by Hydrothermal Exchange D. M. Roy;S. K. Linnehan https://doi.org/10.1038/247220a0
  5. Biomaterials v.17 Fabrication and Characterization of Porous Hydroxyapatite Granules D. M. Liu https://doi.org/10.1016/0142-9612(95)00301-0
  6. Biomaterials v.15 Granulates Based on Calcium Phosphate with Controlled Morphology and Porosity for Medical Applications:Physico-chemical Parameters and Production Technique M. Fabbri;G. C. Celotti;A. Ravaglioli https://doi.org/10.1016/0142-9612(94)90228-3
  7. J. Mater. Sci. Lett. v.15 Control of Pore Geometry on Influencing the Mechanical Property of Porous Hydroxyapatite D. M. Liu
  8. Biomaterials v.24 no.19 Porous $ZrO_2$ Bone Scaffold Coated with Hydroxyapatite with Fluorapatite Intermediate Layer H. W. Kim;S. Y. Lee; C. J. Bae;Y. J. Noh;H. E. Kim;H. M. Kim;J. S. Ko https://doi.org/10.1016/S0142-9612(03)00162-5
  9. J. Am. Ceram. Soc. v.74 no.7 Bioceramics:From Concept to Clinic L. L. Hench https://doi.org/10.1111/j.1151-2916.1991.tb07132.x
  10. Prog. Cryst. Grow. Char. v.4 Apatities in Biological Systems R. Z. Legeros https://doi.org/10.1016/0146-3535(81)90046-0
  11. Am. Ceram. Soc. Bull. v.70 no.1 Calcium Phosphate Ceramics as Bone Substitute C. Lavernia;J. M. Schoenung
  12. J. Mater. Sci. v.31 no.1 Review : Some Physicochemical Aspects of Hydroxyapatite T. S. B. Narasaraju;D. E. Phebe https://doi.org/10.1007/BF00355120
  13. Ceram. Inter. v.23 Influence of Porosity and Pore Size on the Compressive Strength of Porous Hydroxyapatite Ceramics D. M. Liu https://doi.org/10.1016/S0272-8842(96)00009-0
  14. Biomaterials v.16 Influence of Porosity on the Mechanical Resistance of Hydrozyapatite Ceramics Under Compressive Stress J. C. Huec;T. Schaeverbeke;D. Clement;J. Faber;A. Le Rebeller https://doi.org/10.1016/0142-9612(95)98272-G
  15. J. Am. Ceram. Soc. v.85 no.10 Fabrication of Macrochannelled-Hydroxyapatite Bioceramic by Coextrusion Process Y. H. Koh;H. W. Kim;H. E. Kim;J. W. Halloran https://doi.org/10.1111/j.1151-2916.2002.tb00500.x
  16. Biomaterials v.23 Effect of $CaF_2$ on Densification and Properties of Hydroxyapatite-Zirconia Composites for Biomedical Applications H. W. Kim;Y. H. Koh;J. Y. Noh;H. E. Kim;H. M. Kim https://doi.org/10.1016/S0142-9612(02)00150-3