Journal of the Korean Ceramic Society (한국세라믹학회지)

The Korean Ceramic Society (한국세라믹학회)
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Preparation and Characterization of Porous Hydroxyapatite Containing Silicon Derived from Natural Coral

산호 유래 실리콘 함유 다공성 수산화아파타이트의 합성 및 특성 분석

  • 김수룡 (요업기술원 세라믹.건재본부) ;
  • 이윤주 (요업기술원 세라믹.건재본부) ;
  • 송희 (요업기술원 세라믹.건재본부) ;
  • 이종헌 (서울아산병원 정형외과) ;
  • 이강식 (서울아산병원 정형외과) ;
  • 김해중 ((주) 메타바이오메드) ;
  • 김영희 (요업기술원 세라믹.건재본부)
  • Published : 2004.08.01
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Abstract

A porous hydroxyapatite has been prepared using natural coral which resembles human cancellous bone in microstructure. To obtain a biomaterial having a good biocompatibility, substitution of silicon into the hydroxyapatite framework has been attempted. Si substituted hydroxyapatite has been prepared by hydrothermal treatment and solvothermal treatment of the natural coral repeatedly. Si concentration and phase of the Si substituted hydroxyapatite derived from coral have been characterized using a XRD, ICP, and EDS etc. EDS investigation confirmed the presence of silicon in the framework of hydroxyapatite structure.

생체친화성 인공골 개발을 위하여 해면골과 매우 유사한 기공구조를 갖는 천연 산호(CaCO$_3$, aragonite phase)를 수열처리하여 수산화아파타이트 다공체를 제조하였다. 생체 친화성을 증진시키기 위하여 산호를 수열 처리하는 과정에서 실리콘을 치환시키는 실험을 하였다. 수열합성과 solvothermal 방법을 반복적으로 사용하여 실리콘이 치환된 수산화아파타이트를 합성하였으며 이들의 각 온도에 따른 상변화 및 실리콘 농도를 XRD, ICP, EDS 등을 통하여 분석하였다. 분석결과로부터 실리콘이 수산화아파타이트 골격 내에 균일하게 분산되어 있음을 확인하였다.

Keywords

References

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