Journal of the Korean Ceramic Society (한국세라믹학회지)

The Korean Ceramic Society (한국세라믹학회)
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Preparation and Compressive Strength of Hydroxyapatite/Gelatin Composite

Hydroxyapatite/Gelatin복합체의 제조 및 압축강도

  • 신효순 (삼성전기㈜ 중앙연구소) ;
  • 구광모 (경일대학교 신소재ㆍ환경공학과) ;
  • 이석기 (경일대학교 신소재ㆍ환경공학과)
  • Published : 2004.09.01
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Abstract

Hydroxyapatite (HAp)/Gelatin (GEL) homogeneous composites of four different composition ratio were prepared by the co-precipitation process with synthetic HAp and GEL as a binder, HAP/GEL composites were molding by cold isostatic pressing and were sintering by various condition in air. Crystallinity and structure of sintered HAp/GEL composites were investigated by XRD and FTIR. Also, the compressive strength and the fracture surface of sintered specimens were measured by UTM and SEM. HAp/GEL composites showed a phase transformation to partially ${\alpha}$, ${\beta}$-tricalcium phosphate at the sintered condition of 1200$^{\circ}C$ for 3 h. The porosity of sintered body was in the range of 1.2-30.2％. The compressive strength of the sintered specimens was in the range of 16.2-60.1㎫, and its strength of sintered HAp/GEL comosites was higher than expected when the porosity was considered.

합성 수산화아파타이트(HAp)와 바인더로서 젤라틴(GEL)을 사용하여 공침법으로 조성비가 서로 다른 HAp/GEL 균질복 합체 4종을 제조하였고, 이 균질복합체를 냉간정수압법으로 성형한 후 공기중에서 여러조건으로 소결하였다. HAp/GEL composite의 소결체는 XRD 및 FT-IR로 결정성 및 구조를 조사하였고, 또한 소결시편은 만능재료시험기(UTM)로 압축강도를 측정하였으며, 파단된 소결시편의 표면은 SEM으로 관찰하였다 HAp/GEL composite는 120$0^{\circ}C$에서 3시간 소결하였을 경우 부분적인 $\alpha$, $\beta$-tricalcium phosphate로 상전이가 일어났다. 소결체의 기공률은 1.2-30.2% 범위였고, 소결시편의 압축강도는 16.2-60.1㎫ 범위의 값을 나타냄으로써 기공율에 비해 높은 강도를 나타내었다.

Keywords

References

  1. L. L. Hench,'Bioceramics,' J. Am. Ceram. Soc., 81 [7] 1705-27 (1998) https://doi.org/10.1111/j.1151-2916.1998.tb02540.x
  2. W. Weng and J. L. Baptista,'A New Synthesis of Hydroxyapatite,' J. Eur. Ceram. Soc., 17 1151-56 (1997) https://doi.org/10.1016/S0955-2219(96)00215-4
  3. T. Yasue, K. Masuda, Y. Kojima, and Y. Arai, 'Effect of Adsorption of Succinic Acid on the Fonnation of Amorphous Calcium Phosphate(in Jpn.),' J. Ceram. Soc. Jpn., 102 [12] 1122-27 (1994) https://doi.org/10.2109/jcersj.102.1122
  4. R. Z. Wang, F. Z. Cui, H. B. Lu, H. B. Wen, C. L. Ma, and H. D. Li, 'Synthesis of Nanophase Hydroxyapatite/Composite,' J. Mater. Sci. Lett., 14 490-92 (1995) https://doi.org/10.1007/BF00665911
  5. K. Kato, Y. Eika, and Y. Ikada,'In Situ Hydroxyapatite Crystallization for the Formation of Hydroxyapatite/Polymer Composites,' J. Mater. Sci., 32 553-43 (1997)
  6. N. Spanos and P. G. Koutsoukos, 'Hydroxyapatite Precipitation on a Carboxylated Vinyl Chloride-Vinyl Acetate Copolymer' J. Mater. Sci., 36 573-78 (2001) https://doi.org/10.1023/A:1004899832583
  7. S. Mann and G. A. Ozin, 'Synthesis of Inorganic Materials with Complex Fonn,' Nature, 365 499-505 (1996) https://doi.org/10.1038/365499a0
  8. I. Yamaguchi, K. Tokuchi, H. Fukuaki, Y. Koyama, K. Tokakuda, H. Monma, and J. Tanaka, 'Preparation and Microstructure Analysis of Chitosan/lHydroxyapatite Nanocomposites' J. Biomed. Mater. Res., 55 20-7 (2001) https://doi.org/10.1002/1097-4636(200104)55:1<20::AID-JBM30>3.0.CO;2-F
  9. M. C. Chang, 'Heterogeneous Nucleation of Hydroxyapatite- Collagen Nanocomposite' J. Kor. Ceram. Soc., 38 [11] 1030-36 (2001)
  10. Y. J. Yin, F. Zhao, X. F. Song, K. D. Yao, W. W. Lu, and C. Leong, 'Preparation and Characterization of Hydroxyapatite/ Chitosan-Gelatin Network Composite,' J. Appl. Polym. Sci., 77 2929-38 (2000) https://doi.org/10.1002/1097-4628(20000923)77:13<2929::AID-APP16>3.0.CO;2-Q
  11. M. C. Chang, T. Ikoma, M. Kikuchi, and J. Tanaka, 'Preparation of a Porous Hydroxyapatite/Collagen Nanocomposite Using Glutaraldehyde as a Crosslinkage Agent,' J. Mater. Sci. Lett., 20 1199-201 (2001) https://doi.org/10.1023/A:1010914621089
  12. Y. Fujishiro, K. Takahashi, and T. Sato,'Preparation and Compressive Strength of alpha -Tricalcium Phosphate/Gelatin Gel Composite Cement,' J. Biomed. Mater. Res., 54 525-30 (2001) https://doi.org/10.1002/1097-4636(20010315)54:4<525::AID-JBM80>3.0.CO;2-#
  13. S. K. Lee, H. D. Lee, H. S. Shin, and B. K. Lee, 'Preparation and Characterization of Synthetic Hydroxyapatite/ Polyacrylic Acid Homogeneous Composite,' J. Kor. Ceram Soc., 39 [11] 1097-102 (2002) https://doi.org/10.4191/KCERS.2002.39.11.1097
  14. S. K. Lee, K. M. Koo, M. H. Lee, H. D. Lee, and B. K. Lee, 'Sintering Behavior and Mechanical Strength of Hydroxyapatite/Polyacrylic Acid Homogeneous Composite,' J. Kor. Ceram Soc., 40 [6] 566-71 (2003) https://doi.org/10.4191/KCERS.2003.40.6.566
  15. H. Monma and M. Goto, 'Behavior of the $\alpha\leftrightarrow\beta$ , Phase Transfonnation in Tricalcium Phosphate,' Yogyo-KyokaiShi, 91 [10] 473-75 (1983) https://doi.org/10.2109/jcersj1950.91.1058_473
  16. S. R. Kim, B. M. Lee, and Y. K. Park, 'Effect of pH on the Synthesis of Hydroxyapatite,' J. Kor. Ceram. Soc., 28 [11] 885-91 (1991)
  17. K. J. Payne and A. Vies, 'Fourier Transfonn IR SpectroSpectroscopy of Collagen and Gelatin Solutions,' Biopolymers, 27 1749-60 (1988) https://doi.org/10.1002/bip.360271105
  18. J. T. Song, D. W. Ryou, and S. H. Choi, 'Precipitation of Porous Hydroxyapatite Ceramics,' J. Kor. Asso. Crystal Growth, 4 [3] 284-93 (1994)
  19. J. Tian, 'Preparation of Porous Hydroxyapatite,' J. Mater. Sci., 36 3061-66 (2001) https://doi.org/10.1023/A:1017935411108